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Last updated: October 16, 2025View editorial policy

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Differential Diagnosis

  • Single most likely diagnosis
    • Metastatic cancer: The presence of multiple liver lesions, peritoneal deposits, and a lung nodule suggests a malignant process, with metastatic cancer being the most likely diagnosis. The primary site of the cancer is not specified, but the findings are consistent with disseminated disease.
  • Other Likely diagnoses
    • Hepatocellular carcinoma with metastases: Although less likely than metastatic cancer from an unknown primary, hepatocellular carcinoma could explain the liver lesions and peritoneal deposits.
    • Lymphoma: Lymphoma could also present with multiple liver lesions, peritoneal involvement, and lung nodules, although it is less likely than metastatic cancer.
    • Peritoneal carcinomatosis: This condition, characterized by the spread of cancer throughout the peritoneal cavity, could explain the peritoneal deposits and liver lesions.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pheochromocytoma: The small arterial enhancing lesion in the left adrenal gland could be a pheochromocytoma, which is a rare but potentially life-threatening condition if not diagnosed and treated promptly.
    • Abdominal aortic aneurysm rupture: The fusiform abdominal aortic aneurysm is a significant finding that requires monitoring and potential intervention to prevent rupture, which would be catastrophic.
    • Renal cell carcinoma: The left renal calculus and bilateral perinephric fat stranding could be related to a renal cell carcinoma, which would be a significant diagnosis to miss.
  • Rare diagnoses
    • Neuroendocrine tumor: The small arterial enhancing lesion in the left adrenal gland could be a neuroendocrine tumor, although this is less likely than other diagnoses.
    • Sarcoma: The lung nodule and liver lesions could be related to a sarcoma, although this is a rare diagnosis.
    • Tuberculosis: The peritoneal deposits and lung nodule could be related to tuberculosis, although this would be an unusual presentation in an immunocompetent host.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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