What is the clinical significance of Exiguobacterium auranticum in a blood culture?

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From the Research

Clinical Significance of Exiguobacterium auranticum in Blood Culture

  • The clinical significance of Exiguobacterium auranticum in a blood culture is not well-established, but it can be considered a potential contaminant 1.
  • A study found that E. aurantiacum was isolated from a patient with bacteremia after radical prostatectomy, suggesting that it can cause infection in patients, especially those who are immunocompromised 1.
  • The isolation of E. aurantiacum from a blood culture should be evaluated in the context of the patient's clinical presentation and medical history, as it may be a contaminant or a true pathogen 2, 3.
  • Repeat blood cultures may be useful in differentiating true bacteremia from pseudobacteremia, and clinical criteria can be used to evaluate the significance of potential contaminants in blood cultures 2, 3.
  • The clinical impact of extended blood culture incubation for 6 days or more is limited, and a routine extension of the incubation period may be unnecessary, which may help to reduce the detection of contaminants like E. aurantiacum 4.
  • The management of patients with E. aurantiacum in a blood culture should be individualized, taking into account the patient's clinical condition, antibiotic susceptibility, and the results of repeat blood cultures, if available 1, 5.

References

Research

First Isolation of Exiguobacterium aurantiacum in Serbia.

Polish journal of microbiology, 2021

Research

Clinical significance of potential contaminants in blood cultures among patients in a medical center.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2007

Research

Clinical impact of extended blood culture examination: Too much of a good thing.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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