Postnasal drip: This condition, often due to allergies, colds, or sinus infections, leads to the sensation of mucus running down the back of the throat, which can be perceived as a feeling of sputum.

Chronic bronchitis: A type of COPD characterized by chronic inflammation and irritation of the bronchial tubes, leading to excessive mucus production and the sensation of sputum in the throat.
Gastroesophageal reflux disease (GERD): Stomach acid flowing back into the esophagus can cause irritation and lead to the sensation of having sputum or mucus in the throat.
Acute bronchitis: Similar to chronic bronchitis but typically caused by a viral or bacterial infection, leading to temporary inflammation and mucus production.

Pneumonia: Although less common, pneumonia can cause the production of sputum, and in severe cases, it can be life-threatening if not promptly treated.
Lung cancer: Though rare, lung cancer can cause a persistent sensation of sputum due to tumor obstruction or infection, making it crucial not to miss this diagnosis.
Tuberculosis (TB): A bacterial infection that primarily affects the lungs and can cause chronic cough and sputum production, which is critical to diagnose due to its infectious nature and the need for specific treatment.

Cystic fibrosis: A genetic disorder that leads to the production of thick, sticky mucus affecting various organs, including the lungs, and can cause a persistent feeling of sputum in the throat.
Bronchiectasis: A condition characterized by damage to the airways, leading to excessive mucus production and recurrent infections, which can result in the sensation of having sputum in the throat.
Aspiration pneumonia: Occurs when food, liquids, vomit, or saliva is inhaled into the lungs, potentially causing an infection and leading to the sensation of sputum, which is more common in individuals with swallowing disorders.