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Last updated: October 17, 2025View editorial policy

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Differential Diagnosis for Non-itching Erythematous Shallow Ulcer Below Calf

  • Single most likely diagnosis:
    • Venous ulcer: This is the most common cause of leg ulcers, especially in the lower calf area. The non-itching nature and shallow depth are consistent with venous ulcers, which are often caused by poor circulation and venous insufficiency.
  • Other Likely diagnoses:
    • Arterial ulcer: Although typically painful, some arterial ulcers might not be painful, especially in patients with neuropathy. They are usually deeper and more painful than venous ulcers but can present similarly.
    • Traumatic ulcer: An ulcer caused by trauma, such as a burn, abrasion, or other injury, could present as a shallow, erythematous ulcer.
    • Diabetic foot ulcer: While often associated with neuropathy and thus might be painless, diabetic foot ulcers can present in various ways, including as shallow ulcers, especially if caught early.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Malignancy (e.g., basal cell carcinoma, squamous cell carcinoma): Although rare, ulcers caused by skin cancers can present similarly to benign ulcers. Missing a diagnosis of skin cancer could lead to significant morbidity and mortality.
    • Infection (e.g., cellulitis, abscess): While an infection might cause itching, in some cases, especially in immunocompromised patients, it might not. Missing an infection could lead to severe consequences, including sepsis.
    • Vasculitis: Certain types of vasculitis can cause ulcers. This diagnosis is critical to consider because vasculitis can be associated with systemic disease and significant morbidity if not treated promptly.
  • Rare diagnoses:
    • Pyoderma gangrenosum: A rare skin condition that can cause painful (though sometimes painless) ulcers, often with a violaceous border. It's associated with systemic diseases in some cases.
    • Erythema induratum: A form of panniculitis that can cause ulcers, typically on the calves. It's more common in women and can be associated with tuberculosis.
    • Necrobiosis lipoidica: A rare condition that can cause ulcers, typically on the shins. It's associated with diabetes in some cases.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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