What are the criteria for diagnosing a Lisfranc injury?

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Last updated: October 17, 2025View editorial policy

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Diagnostic Criteria for Lisfranc Injury

Lisfranc injuries require a comprehensive imaging approach, with weight-bearing radiographs as the initial step, followed by advanced imaging such as CT or MRI when radiographic findings are inconclusive but clinical suspicion remains high. 1

Clinical Presentation

  • Patients typically present with midfoot pain, swelling, and ecchymosis 2
  • Even subtle injuries can result in significant morbidity if not properly diagnosed and treated 2
  • Lisfranc injuries range from simple capsular ruptures to complex fracture-dislocations 3

Initial Radiographic Evaluation

  • Three-view radiographic study (anteroposterior, oblique, and lateral) should be the first imaging modality 1
  • Weight-bearing radiographs are essential as non-weight-bearing images are unreliable for detecting subtle injuries 1, 4
  • An additional anteroposterior view with 20° craniocaudal angulation improves visualization of the Lisfranc joint 1
  • Bilateral imaging with both feet on anteroposterior radiographs helps detect subtle malalignment when compared to the uninjured side 1

Key Radiographic Findings

  • Diastasis between the first and second metatarsal bases 1
  • Presence of the "fleck" sign (small avulsion fracture at the Lisfranc ligament attachment) 1
  • Displacement of one or more metatarsals from the tarsus 5
  • Conventional radiographs including weightbearing images are not sufficient for routine diagnostic workup of acute hyperflexion injuries 6

Advanced Imaging

  • When radiographs are normal but clinical suspicion remains high, further imaging is warranted 1, 7
  • CT is recommended as the primary imaging technique for:
    • Acute hyperflexion injuries 6
    • High-energy polytrauma 6
    • Patients unable to bear weight 6
    • Demonstrating multiple metatarsal and cuneiform fractures associated with ligamentous Lisfranc injury 6
  • MRI is indicated for:
    • Evaluation of the Lisfranc ligamentous complex when radiographs are normal but clinical suspicion remains high 6, 1
    • Direct visualization of ligamentous injuries 3
    • 3-D volumetric acquisitions have proven superiority over orthogonal proton density fat-suppressed imaging 6
    • High correlation with intraoperative findings for unstable Lisfranc injuries 6, 4

Special Considerations

  • In polytrauma patients, approximately 25% of midfoot fractures identified on CT are overlooked on radiographs 1
  • Patients with neuropathy require special attention as they may be able to bear weight despite fractures 1
  • Purely ligamentous injuries without diastasis are particularly challenging to diagnose and may require MRI 1
  • Ultrasound may have a limited role in Lisfranc injury evaluation but is not considered a primary diagnostic tool 1

Common Pitfalls to Avoid

  • Relying solely on non-weight-bearing radiographs can lead to missed diagnoses 1
  • Delay in diagnosis has a negative impact on outcome 7
  • Failure to obtain advanced imaging when radiographs are inconclusive but clinical suspicion remains high 2
  • Overlooking subtle injuries that can lead to chronic pain, mobility challenges, and post-traumatic osteoarthritis 2, 8

Diagnostic Algorithm

  1. Initial assessment with weight-bearing three-view radiographs when possible 1
  2. If radiographs are inconclusive but clinical suspicion remains:
    • Obtain CT for detailed osseous evaluation and detection of nondisplaced fractures 1, 2
    • Consider MRI for direct visualization of ligamentous injuries 1, 3
  3. Assess stability with weight-bearing radiographs when possible 7
  4. Consult orthopedic surgery for all diagnosed Lisfranc injuries 2

References

Guideline

Diagnostic Criteria for Lisfranc Fracture of the Foot

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

High risk and low incidence diseases: Lisfranc injury.

The American journal of emergency medicine, 2024

Research

Imaging Diagnostics of Lisfranc Joint Injuries.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2025

Guideline

Treatment of Lisfranc Dislocation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Lisfranc injuries.

Injury, 2015

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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