What is the recommended dose of Atarax (hydroxyzine) syrup for a 10-month-old baby?

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Recommended Dosage of Atarax (Hydroxyzine) Syrup for a 10-Month-Old Baby

For a 10-month-old baby, the recommended dose of Atarax (hydroxyzine) syrup (10 mg/5mL) is 0.6 mg/kg of body weight per dose. 1

Dosing Guidelines for Hydroxyzine in Infants

  • For infants under 6 years of age, hydroxyzine should be administered at a total daily dose of 50 mg divided throughout the day 1
  • For a 10-month-old specifically, the FDA-approved dosing is 0.6 mg/kg per dose when used as a sedative 1
  • The dosage should be adjusted according to the patient's response to therapy 1

Calculating the Specific Dose

To calculate the exact dose for a 10-month-old:

  • Multiply the baby's weight (in kg) by 0.6 mg/kg 1
  • For example:
    • If the baby weighs 8 kg: 8 kg × 0.6 mg/kg = 4.8 mg per dose
    • Using the 10 mg/5mL concentration: 4.8 mg would equal approximately 2.4 mL per dose

Administration Considerations

  • Hydroxyzine syrup can be administered without regard to meals 1
  • The medication is typically administered in divided doses throughout the day 1
  • The frequency of administration depends on the indication:
    • For pruritus (itching): typically divided into 3-4 doses per day 1, 2
    • For sedation: typically given as a single dose 1

Efficacy and Safety Considerations

  • In pediatric studies, hydroxyzine at 0.7 mg/kg was shown to effectively suppress pruritus for up to 24 hours, with peak effect between 2-12 hours after administration 2
  • The elimination half-life of hydroxyzine in children increases with age, with a mean half-life of approximately 7.1 hours 2
  • The most common adverse effect reported in children is sedation 2

Important Precautions

  • Start with the lowest effective dose and adjust based on clinical response 1
  • Monitor for excessive sedation, which is the most common side effect 2
  • Avoid combining with other central nervous system depressants, as hydroxyzine can cause significant drowsiness 3
  • Be aware that hydroxyzine may impair cognitive function, which is particularly important to consider when caring for young children 3

Follow-up Recommendations

  • Evaluate the clinical response within 48-72 hours of initiating therapy 4
  • If the desired therapeutic effect is not achieved, consult with the prescribing physician before adjusting the dose 1
  • Regular follow-up is recommended to assess ongoing need for the medication and to monitor for any adverse effects 2

References

Research

Hydroxyzine in Impaired Driving Investigations.

Journal of analytical toxicology, 2025

Guideline

Amoxicillin Dosage and Administration for Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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