Menstrual Abnormalities and Normal Menstrual Cycle Duration
The normal menstrual cycle typically lasts between 21 and 35 days, with eumenorrhea defined as regular cycles occurring at intervals within this range. 1
Normal Menstrual Cycle Parameters
- Cycle length: 21-35 days in adult women 1
- Adolescent cycle length: 21-45 days 1
- Menses duration: Typically 5 days, but can vary 2
- Fertile phase: From 5 days before to the day of ovulation 2
- Ovulation: Generally occurs during days 9-20 in a standard 28-day cycle 1
- Cycle variation: Decreases with age, with the 5th-95th percentile range narrowing from 23-35 days in ages 15-19 to 23-30 days in ages 40-44 3
Common Menstrual Abnormalities
Cycle Length Abnormalities
- Polymenorrhea: Cycle length less than 21 days 3
- Oligomenorrhea: Cycles longer than 35 days 1, 3
- Amenorrhea:
Bleeding Pattern Abnormalities
- Hypomenorrhea: Abnormally light bleeding 1
- Menorrhagia/Hypermenorrhea: Abnormally heavy bleeding 1
- Metrorrhagia: Irregular bleeding between periods 4
- Premenstrual and postmenstrual spotting: Light bleeding before or after the main menstrual flow 1
Cycle Regularity Abnormalities
- Irregular cycles: Cycles varying by more than 14 days in length 3
- Subclinical menstrual defects: Abnormalities that may not be apparent without hormonal testing 1
Health Implications of Menstrual Abnormalities
- Metabolic implications: Menstrual irregularities are associated with metabolic syndrome, coronary heart disease, and type 2 diabetes 4
- Bone health: Estrogen deficiency from amenorrhea can lead to reduced bone density and increased risk of osteoporosis 5
- Fertility: Irregular cycles can indicate ovulatory dysfunction and potential fertility issues 4, 6
- Pregnancy outcomes: Irregular menstruation is associated with increased risk of pregnancy-related hypertensive disorders and adverse obstetric outcomes 4
- Quality of life: Menstrual disorders can significantly impact physical, mental, and social well-being 4
Relative Energy Deficiency in Sport (RED-S) and Menstrual Function
- Female Athlete Triad: The interrelationship between energy availability, bone health, and menstrual function 1
- Energy availability threshold: Energy availability below 30 kcal/kg fat-free mass per day is associated with menstrual disturbances 1
- Prevalence: Menstrual disorders affect up to 69% of dancers and collegiate long-distance runners 1
- Risk factors: Rapid weight loss, low body fat, high training volume, and psychological stress 1
Clinical Significance
- Menstrual cycle irregularities should be considered an important health indicator requiring evaluation 4, 5
- Regular monitoring of menstrual patterns throughout adolescence and adulthood can help identify potential health concerns early 5
- Evaluation of amenorrhea lasting more than 3 months is warranted, even in adolescents, as this exceeds the 95th percentile for cycle intervals 5
- Hormone monitoring technologies can provide more precise cycle tracking than relying on calendar-based estimates alone 6
Understanding normal menstrual cycle parameters and recognizing abnormalities is essential for early identification of potential health concerns and appropriate clinical intervention.