Differential Diagnosis for Breast Lump

• Single most likely diagnosis
  • Fibroadenoma: This is a common benign breast tumor, especially in young women. It is usually a firm, mobile, and painless lump.
• Other Likely diagnoses
  • Cyst: Breast cysts are fluid-filled sacs that can occur in the breast. They are often tender and can fluctuate in size with the menstrual cycle.
  • Fibrocystic changes: These are benign changes in the breast tissue that can cause lumps, tenderness, and a rope-like texture.
  • Lipoma: A benign tumor composed of fat tissue, which can occur in the breast.
  • Breast abscess: An infection of the breast tissue, which can cause a painful lump.
• Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
  • Breast cancer: Although less common, breast cancer is a critical diagnosis to consider, especially in older women or those with a family history.
  • Phyllodes tumor: A rare tumor that can be benign, borderline, or malignant, and may present as a rapidly growing lump.
  • Inflammatory breast cancer: A rare and aggressive form of breast cancer that can cause a lump, redness, and swelling of the breast.
• Rare diagnoses
  • Hamartoma: A rare benign tumor of the breast that can cause a lump.
  • Pseudoangiomatous stromal hyperplasia (PASH): A rare benign condition that can cause a lump in the breast.
  • Granulomatous mastitis: A rare inflammatory condition that can cause a lump and other symptoms in the breast.