Telmisartan Dosing After Multiple Same-Day Doses
You should wait until tomorrow morning to take your next 80mg dose of telmisartan, following a once-daily dosing schedule. 1
Understanding Telmisartan Dosing
- Telmisartan is typically administered once daily, with the usual dose being 40-80mg 1
- The FDA-approved dosing for telmisartan is once daily, not twice daily, regardless of blood pressure control 1
- Most of the antihypertensive effect becomes apparent within 2 weeks of starting treatment, with maximal reduction generally attained after 4 weeks 1
Managing Your Current Situation
- Taking two 40mg doses in one day (total 80mg) means you've already received your full daily dose 1
- Taking another dose tomorrow morning would lead to excessive dosing within a 24-hour period 1
- The terminal elimination half-life of telmisartan is approximately 24 hours, meaning the medication remains active in your system 2
Blood Pressure Control Considerations
- Telmisartan provides effective blood pressure control throughout the entire 24-hour dosing interval, even at the end of the dosing period 2
- Studies show telmisartan maintains significant blood pressure-lowering effects for the full 24-hour period, with inhibitory effects still observable at 48 hours after administration 3
- Even after a missed dose, telmisartan 80mg provides superior blood pressure control compared to some other ARBs 2
Next Steps
- Resume your regular once-daily dosing schedule tomorrow morning 1
- If you experience persistent angina or uncontrolled hypertension, contact your healthcare provider for potential medication adjustments 4
- Your provider may consider adding a complementary agent from a different class if blood pressure remains uncontrolled on telmisartan monotherapy 5
Important Monitoring
- Monitor your blood pressure regularly to ensure adequate control 4
- Be alert for symptoms of hypotension (dizziness, lightheadedness) which could occur with excessive dosing 1
- Watch for signs of hyperkalemia (weakness, irregular heartbeat), especially if you have kidney disease or take potassium supplements 1
Remember that telmisartan's long duration of action helps maintain blood pressure control even at the end of the 24-hour dosing interval 6, so taking your next dose tomorrow morning will provide continuous coverage without risking overdosage.