What are the treatment options for a condition treated at the Mayo Clinic?

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Last updated: October 17, 2025View editorial policy

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Treatment Options at the Mayo Clinic: A Comprehensive Approach

The Mayo Clinic offers a multidisciplinary approach to treatment that prioritizes patient-centered care through coordinated specialist teams, personalized treatment plans, and evidence-based interventions tailored to specific conditions.

Core Treatment Principles

  • Treatment at Mayo Clinic involves multidisciplinary teams including medical, radiation, surgical and imaging specialists, palliative care experts, and psychosocial support professionals working together to provide comprehensive care 1
  • Patient preferences are actively incorporated into treatment decisions, with realistic treatment goals discussed from the beginning of care 1
  • Specialist nurses often provide crucial support, coordination, and continuity of care for patients with complex conditions 1

Condition-Specific Treatment Approaches

Pain Management for Inflammatory and Degenerative Conditions

  • Physical activity and exercise are recommended as first-line treatments, with referral to physiotherapists for individually tailored graded exercise programs when needed 1
  • Orthotic devices (splints, braces, insoles) and assistive devices are offered when pain impedes daily functioning 1
  • Psychological and social interventions are provided when these factors interfere with effective pain management 1
  • Sleep interventions are recommended when sleep disturbance is reported, with education about sleep hygiene practices 1
  • Weight management options are discussed with patients when obesity contributes to pain and disability 1

Cancer Treatment (e.g., Breast Cancer)

  • Isolated locoregional recurrences are treated with curative intent whenever possible 1
  • Systemic treatment options include endocrine therapy, chemotherapy, bone-directed agents, and targeted biological agents 1
  • Treatment selection considers factors like previous therapies and response, disease-free interval, tumor characteristics, and patient preferences 1
  • For metastatic disease, palliative care is integrated with disease-directed therapy to maintain/improve quality of life 1

Multiple Myeloma Management

  • Treatment options are tailored based on prior treatments and duration of response 1
  • For previously treated multiple myeloma, options include systemic therapy, autologous hematopoietic cell transplantation for eligible patients, or clinical trials 1
  • Patients who had autologous transplantation with durable response may be considered for a second transplantation at relapse 1
  • Risk-adapted therapy approaches are used, with different regimens for standard-risk, intermediate-risk, and high-risk disease 1

Mechanical Circulatory Support

  • Patients with mechanical circulatory support devices receive comprehensive care including device parameter monitoring, driveline management, and physical/occupational therapy 1
  • Evidence-based heart failure medical therapies are continued in patients with mechanical support devices 1
  • Palliative care involvement is recommended during evaluation and throughout treatment 1

Osteoarthritis Management

  • Initial treatment includes self-management programs with regular exercise, weight reduction for overweight patients, and bracing/adaptive equipment as needed 1
  • Pharmacotherapy options include topical agents (NSAIDs, capsaicin) for knee OA, acetaminophen, and oral NSAIDs 1
  • Physical therapy referral is considered based on pain severity and functional limitations 1
  • A structured management algorithm guides treatment progression from initial approaches to more advanced interventions 1

Patient Safety Considerations

  • Treatment plans incorporate patient safety as an essential component, with protocols to reduce the risk of adverse events 2
  • Priority is given to addressing both serious and common problems that impact patient outcomes and resource utilization 3
  • Transparency, care integration, patient engagement, and team-based approaches are fundamental to achieving meaningful safety improvements 4

Clinical Decision Making

  • Evidence-based approaches guide treatment selection, with consideration of both benefits and risks for each intervention 5
  • When multiple treatment options are indicated, multidisciplinary interventions are considered, especially when monotherapy has failed 1
  • Clinical trials are prioritized and offered to eligible patients whenever available 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Setting priorities for patient safety.

Quality & safety in health care, 2002

Research

Transforming healthcare: a safety imperative.

Quality & safety in health care, 2009

Research

Making health care safer: a critical analysis of patient safety practices.

Evidence report/technology assessment (Summary), 2001

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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