ABI Testing for Lower Extremity Wounds: WOCN Recommendations
The WOCN Society does not recommend ABI testing for every lower extremity wound, but rather recommends it as part of a comprehensive vascular assessment for patients with suspected arterial disease or risk factors for PAD. 1
Indications for ABI Testing in Lower Extremity Wounds
ABI testing is recommended as a first-line test for patients with suspected lower extremity PAD, defined as individuals with:
- Exertional leg symptoms
- Nonhealing wounds
- Age ≥70 years
- Age 50-69 years with a history of smoking or diabetes 2
ABI should be performed in patients with history or physical examination findings suggestive of PAD to establish the diagnosis 2
ABI measurement is reasonable in patients at increased risk of PAD even without history or physical examination findings suggestive of PAD 2
Limitations of ABI in Wound Assessment
ABI may be normal in nearly one-quarter of patients with chronic limb-threatening ischemia, making it unreliable as the sole assessment tool 3
The concordance between ABI and toe pressure/toe-brachial index among patients with chronic limb-threatening ischemia is poor, with only 58% of patients who meet criteria for abnormal toe pressures presenting with abnormal ABIs 3
ABI may not be accurate when systolic blood pressure cannot be abolished by inflation of an air-filled blood pressure cuff (noncompressible pedal arteries), as occurs in some diabetic or elderly individuals 2
Comprehensive Vascular Assessment Approach
For optimal wound assessment, a more comprehensive approach is recommended:
Initial ABI measurement for all patients with lower extremity wounds 3
- If ABI ≤0.90: PAD is confirmed, but additional testing is needed to assess wound healing potential
- If ABI >1.40: Vessels are noncompressible, and TBI is mandatory
Additional testing when indicated:
Perfusion assessment measures:
Clinical Impact of Early ABI Testing
- Early ABI testing (<30 days from wound identification) has been associated with:
- Quicker time to vascular referral (13 days vs. 91 days)
- Faster wound healing (117 days vs. 287 days)
- Potentially lower amputation rates 5
Common Pitfalls to Avoid
Relying solely on ABI may miss significant arterial disease in patients with diabetes or advanced age due to arterial calcification causing falsely elevated readings 3, 6
Normal range ABI outcomes (0.9-1.4) cannot be taken to infer the absence of LEAD; ABI has a sensitivity of only 72.3% and specificity of 69.3% when using duplex ultrasound as a benchmark 6
Failure to perform a pulse exam when a wound is identified may delay appropriate vascular assessment and intervention 5