What is the recommended therapy for non-venomous spider bites?

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Therapy for Non-Venomous Spider Bites

For non-venomous spider bites, thoroughly irrigate the wound with copious amounts of clean water, apply antibiotic ointment, and cover with a clean occlusive dressing. 1

Initial Management

  • Thoroughly irrigate the bite wound with a large volume of warm or room temperature potable water until there is no foreign matter in the wound 1
  • Apply a clean barrier (such as a thin towel) between ice and skin when applying ice for pain relief 1
  • Cover the wound with antibiotic ointment or cream and a clean occlusive dressing to improve healing and reduce infection risk 1

Pain Management

  • Over-the-counter acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) are effective for managing local pain 2
  • Ice application to the bite site provides local pain relief (with a barrier between ice and skin) 1, 3
  • If skin is intact, topical lidocaine can be applied for pain relief 4

When to Seek Medical Care

  • Seek medical attention if:
    • Pain extends beyond the bite site or becomes severe 4
    • Pain is not controlled by over-the-counter medications 4
    • An open wound develops 5
    • Signs of infection appear (progressive erythema, purulent discharge, fever) 5
    • Systemic symptoms develop (difficulty breathing, muscle rigidity, dizziness, confusion) 5, 4

Common Pitfalls to Avoid

  • Do not apply suction to the bite site as this is ineffective and potentially harmful 3
  • Do not apply tourniquets or pressure immobilization bandages as these may worsen tissue injury 3
  • Do not place objects in the mouth of someone having a seizure (if severe envenomation occurs) as this may cause dental damage or aspiration 1
  • Do not assume antibiotics are needed for swelling around the bite site, as swelling is typically caused by mediator release, not infection 5

Special Considerations for Specific Non-Venomous Spider Bites

  • Most non-venomous spider bites cause limited swelling, itching, pain, and redness 2
  • Remove rings and other constricting objects from the bitten extremity as swelling may occur 3
  • For persistent or non-healing wounds (though rare with non-venomous spiders), hyperbaric oxygen therapy may be considered in select cases 6

Follow-up Care

  • Most patients with local symptoms only will recover completely within 24-48 hours 5
  • Continue pain management with over-the-counter medications as needed for several days 5
  • Monitor for signs of secondary infection, which would require prompt medical attention 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Managing arthropod bites and stings.

The Physician and sportsmedicine, 1998

Guideline

Treatment for Brown Recluse Spider Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment for Black Widow Spider Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment for Scorpion Stings

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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