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Last updated: October 18, 2025View editorial policy

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Differential Diagnosis for Edematous Arytenoids

  • Single most likely diagnosis
    • Acute Laryngitis: This is the most common cause of edematous arytenoids, often resulting from viral infections, voice abuse, or irritants like smoke. The inflammation leads to swelling of the arytenoid cartilages.
  • Other Likely diagnoses
    • Gastroesophageal Reflux Disease (GERD): Stomach acid reflux can cause chronic inflammation and edema of the arytenoids due to the acidic environment.
    • Allergic Reactions: Allergens can trigger an allergic response, leading to edema and swelling in the laryngeal area, including the arytenoids.
    • Trauma: Direct injury to the larynx, such as from intubation or external trauma, can cause edema of the arytenoids.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Epiglottitis: Although less common, epiglottitis can cause significant swelling that might affect the arytenoids indirectly and can lead to airway obstruction, which is a medical emergency.
    • Angioedema: A severe allergic reaction that can cause rapid swelling of the airways, including the arytenoids, potentially leading to airway obstruction.
  • Rare diagnoses
    • Sarcoidosis: A systemic disease that can cause granulomatous inflammation in various parts of the body, including the larynx, leading to edema of the arytenoids.
    • Amyloidosis: A condition characterized by the deposition of amyloid proteins in various tissues, which can rarely affect the larynx and cause edema of the arytenoids.
    • Relapsing Polychondritis: An autoimmune disease that can cause inflammation and destruction of cartilaginous structures, including those in the larynx, leading to edema and other complications.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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