What are the post-procedure instructions for patients receiving Botox (Botulinum toxin) injections?

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Last updated: October 18, 2025View editorial policy

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Discharge Instructions for Botox Injections

Patients who have received Botox injections should follow specific post-procedure care instructions to maximize benefits and minimize potential complications.

Key Post-Procedure Instructions

  • Avoid rubbing or massaging the treated area for 24 hours after injection to prevent spreading of the toxin to adjacent muscles 1, 2

  • Remain upright for 4 hours after treatment and avoid lying down or bending over to minimize risk of toxin migration 2, 3

  • Gently exercise the treated muscles (such as frowning, raising eyebrows, or smiling depending on injection site) for 1-2 hours after injection to help the toxin bind at the neuromuscular junction 2

  • Avoid strenuous physical activity for 24 hours after treatment to prevent increased blood flow that could potentially spread the toxin 2, 3

  • Avoid alcohol consumption for 24 hours after treatment as it may increase the risk of bruising 2

  • Apply cold compresses to the injection sites if needed to reduce pain, swelling or bruising 2

Potential Side Effects to Monitor

  • Mild and transient side effects are common and typically resolve within a few days without treatment 1, 4:

    • Localized pain at injection sites
    • Bruising or redness
    • Swelling
    • Headache
    • Mild flu-like symptoms
  • Contact your healthcare provider immediately if you experience 5, 2:

    • Difficulty swallowing or speaking
    • Respiratory problems
    • Muscle weakness beyond the treatment area
    • Severe headache
    • Vision problems or eye pain
    • Allergic reactions (rash, itching, wheezing)

Special Considerations for Specific Treatment Areas

Upper Face Treatment

  • Watch for eyelid or eyebrow ptosis (drooping), which is the most common complication with upper face injections 3
  • Report any visual disturbances such as double vision (diplopia) immediately 3
  • Use prescribed eye drops if recommended by your provider for temporary eyelid ptosis 2

Neck and Lower Face Treatment

  • Monitor for difficulty swallowing (dysphagia) which may occur with neck or lower face injections 5
  • Report any changes in voice or speech that persist beyond a few days 6

For Hyperhidrosis (Excessive Sweating)

  • Expect gradual reduction in sweating over 1-2 weeks following treatment 2
  • Continue using antiperspirants as directed by your provider

Follow-up Care

  • Schedule a follow-up appointment 2 weeks after treatment to assess results 6
  • Results typically last 3-6 months depending on the treatment area and individual factors 6, 4
  • Do not receive additional Botox treatments from another provider without informing them of your recent injection 7

When to Seek Medical Attention

  • Contact your healthcare provider immediately if you experience symptoms suggesting systemic spread of toxin, such as generalized muscle weakness, difficulty breathing, or swallowing problems 5
  • Seek emergency care if you develop signs of a severe allergic reaction including difficulty breathing, severe swelling, or hives 7, 2

Remember that while serious complications from cosmetic Botox are rare, prompt reporting of concerning symptoms is important to ensure your safety and optimal results.

References

Research

The whole truth about botulinum toxin - a review.

Postepy dermatologii i alergologii, 2020

Research

BOTOX: a review.

Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses, 2003

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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