Differential Diagnosis for Enteritis with Limb Pain
Single Most Likely Diagnosis
- Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease or ulcerative colitis can cause enteritis and may be associated with extraintestinal manifestations, including limb pain due to arthritis or other musculoskeletal issues.
Other Likely Diagnoses
- Irritable Bowel Syndrome (IBS): While primarily causing gastrointestinal symptoms, IBS can sometimes be associated with extraintestinal symptoms, including musculoskeletal pain.
- Infectious Gastroenteritis: Certain infections can cause both gastrointestinal and systemic symptoms, including limb pain, especially if the infection leads to a systemic inflammatory response.
- Food Intolerance or Allergy: Conditions like celiac disease or lactose intolerance can cause gastrointestinal symptoms and may also lead to systemic symptoms, including joint pain, due to inflammation or malabsorption.
Do Not Miss Diagnoses
- Systemic Lupus Erythematosus (SLE): An autoimmune disease that can cause a wide range of symptoms, including gastrointestinal issues and joint pain. Missing this diagnosis could lead to significant morbidity.
- Rheumatoid Arthritis: While primarily an autoimmune disease affecting the joints, rheumatoid arthritis can also cause gastrointestinal symptoms and must be considered to avoid missing a potentially treatable condition.
- Vasculitis: Conditions like Henoch-Schönlein purpura can cause both gastrointestinal symptoms (enteritis) and limb pain due to vasculitic changes.
Rare Diagnoses
- Ehlers-Danlos Syndrome: A group of disorders that affect connective tissues supporting the skin, bones, blood vessels, and many other organs and tissues. Gastrointestinal symptoms and joint hypermobility can occur.
- Whipple's Disease: A rare, systemic bacterial infection that can cause malabsorption, weight loss, joint pain, and other systemic symptoms.
- Sarcoidosis: An inflammatory disease that can affect multiple organs in the body, including the gastrointestinal tract and joints, though gastrointestinal involvement is less common.