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Differential Diagnosis for Sores on Tongue in a Toddler

Single Most Likely Diagnosis

  • Recurrent Hand, Foot, and Mouth Disease (HFMD): The toddler had HFMD 1 month ago, and it's possible for the disease to recur, especially if exposed to the virus again. The sores on the tongue could be a manifestation of the recurrence.

Other Likely Diagnoses

  • Herpes Simplex Virus (HSV) Infection: HSV can cause oral ulcers, including on the tongue, and is common in toddlers.
  • Aphthous Ulcers: Also known as canker sores, these are common in children and can appear on the tongue.
  • Trauma: Accidental biting or other forms of trauma to the tongue can cause sores.
  • Viral Gingivostomatitis: Caused by viruses such as HSV or coxsackievirus, this condition can lead to sores on the tongue and other parts of the mouth.

Do Not Miss Diagnoses

  • Herpangina: Although less common, herpangina is a serious condition that can cause severe pain and difficulty swallowing, and it's essential to rule it out.
  • Autoimmune Disorders (e.g., Pemphigus): Although rare in toddlers, autoimmune disorders can cause oral ulcers and are critical to diagnose early.
  • Immunodeficiency: Underlying immunodeficiency can predispose to recurrent or severe infections, including those causing oral ulcers.

Rare Diagnoses

  • Behçet's Disease: A rare condition that can cause oral ulcers, although it's more common in older children and adults.
  • Erythema Multiforme: A rare skin condition that can cause oral ulcers, often in response to an infection or medication.
  • Leukemia: Although extremely rare, leukemia can cause oral ulcers and is a diagnosis that should be considered if other symptoms such as fever, fatigue, or weight loss are present.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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