Diagnostic Tests for Greater Trochanteric Pain Syndrome (GTPS)
The diagnosis of Greater Trochanteric Pain Syndrome (GTPS) requires a combination of clinical examination, imaging studies, and diagnostic injections, with MRI being the preferred imaging modality when radiographs are negative or nondiagnostic.
Clinical Examination Tests
- The 30-second single-leg stance test has excellent sensitivity (100%) and specificity (97.3%) for diagnosing gluteal tendinopathy in patients with GTPS 1
- The resisted external derotation test in supine position (hip flexed 90 degrees) demonstrates 88% sensitivity and 97.3% specificity for identifying tendinous lesions and bursitis in GTPS 1
- Trendelenburg's sign is the most accurate physical examination finding for predicting gluteus medius tears, with a sensitivity of 72.7% and specificity of 76.9% 2
- Palpation over the greater trochanter to elicit pain is a key clinical examination technique for diagnosing GTPS 3
Imaging Studies
Initial Imaging
- Plain radiographs should be obtained first to rule out other causes of hip pain, though they have limited sensitivity for soft tissue pathology 4, 5
- Radiographs help exclude hip joint arthropathy and other bony abnormalities that may mimic GTPS 5
Advanced Imaging
- MRI is the preferred imaging modality for evaluating soft tissue abnormalities around the hip when radiographs are negative or nondiagnostic 4
- MRI can comprehensively assess peritrochanteric structures including:
- Ultrasound is effective for detecting:
- Ultrasound can identify specific pathological features including:
- Tendon matrix changes
- Calcifications (most commonly in gluteus medius)
- Tendon thickness
- Hypoechogenicity
- Partial tears 6
Diagnostic Injections
- Diagnostic injection with local anesthetic (lidocaine) into the trochanteric bursa provides both diagnostic confirmation and potential therapeutic benefit 4, 5
- A positive response to injection (pain relief) confirms GTPS as the source of pain 4
- Ultrasound guidance improves the accuracy of diagnostic injections 5
Diagnostic Challenges
- Differentiation between trochanteric bursitis and gluteus medius/minimus tendinosis can be challenging on imaging, and these conditions frequently coexist 4, 5
- In patients with hip prostheses, extracapsular disease associated with adverse reactions to metal debris could be misinterpreted as trochanteric bursitis 5
- MRI studies show that GTPS often involves gluteus medius tendinopathy (97.7% of cases) and gluteus minimus tendinopathy (61.4% of cases) rather than isolated trochanteric bursitis 6, 2
- Trochanteric bursal distension is uncommon (found in only 40.9% of patients) and rarely occurs in the absence of gluteal tendon pathology 6, 2
Diagnostic Algorithm
Perform clinical examination including:
Obtain plain radiographs to exclude hip joint pathology and other bony abnormalities 4, 5
If radiographs are negative or nondiagnostic, proceed with:
Consider diagnostic injection with local anesthetic for confirmation when clinical and imaging findings are equivocal 4, 5