From the Research
Gallivardin's phenomenon in aortic stenosis is caused by the transmission of high-frequency components of the systolic murmur to the apex of the heart, while the low-frequency components remain at the base. This phenomenon is specifically associated with severe calcific aortic stenosis, where the calcified and stiffened aortic valve creates turbulent blood flow and generates these high-frequency vibrations 1. As blood forcefully passes through the narrowed aortic valve opening, it creates a jet that produces both low and high-frequency sounds. The high-frequency component can mimic mitral regurgitation at the apex, potentially leading to diagnostic confusion. This phenomenon typically indicates advanced aortic stenosis with significant valve calcification and is more common in elderly patients with degenerative aortic valve disease 2. Some key points to consider in the management of aortic stenosis include:
- The incidence of aortic stenosis increases with age, affecting up to 10% of the population by the eighth decade 3
- Proper management requires an understanding of the physiology and criteria used to define disease severity
- There is no effective pharmacologic treatment, and surgical aortic valve replacement or transcatheter aortic valve replacement are the primary treatment options 4
- Recognition of Gallivardin's phenomenon is important for accurate diagnosis and appropriate management of aortic stenosis, as it can help identify patients with severe calcific aortic stenosis who may require prompt intervention 5. In terms of management, the decision between surgical aortic valve replacement and transcatheter aortic valve replacement should be made on a case-by-case basis, taking into account the patient's individual characteristics, preferences, and clinical indicators 1. Overall, accurate diagnosis and timely management of aortic stenosis are crucial to improve patient outcomes and reduce morbidity and mortality.