What is the proper way to take FEMOSTON 2/10 (Estradiol/Hormone Replacement Therapy) tablet?

How to Take FEMOSTON 2/10 Tablet

FEMOSTON 2/10 should be taken as a sequential regimen with the white tablets (containing 2 mg estradiol) taken for the first 14 days, followed by the gray tablets (containing 2 mg estradiol and 10 mg dydrogesterone) for the remaining 14 days of each 28-day cycle, without interruption between packs.

Administration Instructions

• Take one tablet daily at approximately the same time each day 1
• Follow the sequential regimen indicated on the package: white tablets for days 1-14, followed by gray tablets for days 15-28 1, 2
• Take the tablets continuously without interruption between packs 1
• If you miss a tablet, take it as soon as possible within 24 hours; if more than 24 hours have passed, do not take the missed tablet and continue with your next scheduled tablet 1

Duration of Treatment

• FEMOSTON 2/10 should be used at the lowest effective dose for the shortest duration needed to control symptoms 2
• You and your healthcare provider should regularly evaluate (every 3-6 months) whether continued treatment is necessary 2
• For menopausal symptoms, treatment should be discontinued as promptly as possible once symptoms are controlled 2

Expected Effects

• FEMOSTON 2/10 effectively treats moderate to severe menopausal symptoms including hot flashes and vaginal dryness 2, 3
• The sequential regimen will typically result in regular withdrawal bleeding during the latter part of each cycle 1, 4
• Approximately 71% of women may experience no bleeding during the first cycle, increasing to about 80% by the end of one year of treatment 4

Important Considerations

• FEMOSTON 2/10 should not be used if you have:

  • Unusual vaginal bleeding that has not been evaluated 2
  • Current or past history of breast cancer or other estrogen-dependent cancers 2
  • History of stroke, heart attack, or blood clots within the past year 2
  • Active liver disease 2
  • Known hypersensitivity to any components of the medication 2

• Regular follow-up with your healthcare provider is essential:

  • Visit your doctor at least once a year for a check-up while using FEMOSTON 2
  • Report any unusual vaginal bleeding immediately 2
  • Have regular breast examinations and mammograms as recommended 2

Potential Benefits Beyond Symptom Control

• FEMOSTON may help reduce the risk of postmenopausal osteoporosis 2, 5
• Studies have shown positive effects on lipid profiles with reductions in total cholesterol and LDL-cholesterol and increases in HDL-cholesterol 6, 5
• Some evidence suggests improvements in cardiovascular parameters including blood pressure and vascular resistance 7, 5

Common Side Effects

• Headache, breast pain, and nausea may occur 2
• Irregular vaginal bleeding or spotting, particularly during the first few months of treatment 2, 4
• Stomach/abdominal cramps and bloating 2

Remember to contact your healthcare provider immediately if you experience severe headaches, chest pain, shortness of breath, leg pain, changes in vision, or unusual vaginal bleeding 2.