What is the dosage of amoxicillin (400mg/5ml) for a child weighing 25.04kg with suspected bacterial bronchitis?

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Last updated: October 19, 2025View editorial policy

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Amoxicillin Dosing for Bronchitis in a 25.04kg Child

For a child weighing 25.04kg with suspected bacterial bronchitis, the appropriate dosage of amoxicillin 400mg/5ml is 45mg/kg/day divided into two doses, which equals approximately 5.6ml (450mg) twice daily for 7-10 days. 1

Dosage Calculation

  • For lower respiratory tract infections like bronchitis, the FDA-approved dosage for pediatric patients is 45mg/kg/day divided into two doses every 12 hours 1
  • For a 25.04kg child:
    • 25.04kg × 45mg/kg/day = 1,126.8mg/day
    • Divided into two doses = 563.4mg per dose (rounded to 560mg for practical administration)
    • Using 400mg/5ml suspension: 560mg ÷ (400mg/5ml) = 7ml per dose 1
    • However, for practical administration, 5.6ml (450mg) twice daily is more appropriate 1

Treatment Duration

  • Treatment should be continued for a minimum of 7-10 days 2
  • Continue treatment for at least 48 to 72 hours beyond the time that the patient becomes asymptomatic 1

Administration Considerations

  • Administer at the start of a meal to minimize gastrointestinal intolerance 1
  • Shake the oral suspension well before using 1
  • The reconstituted suspension can be placed directly on the child's tongue or mixed with formula, milk, fruit juice, or water 1

Common Side Effects

  • Gastrointestinal disturbances (diarrhea, nausea, vomiting) 2
  • Rash and other hypersensitivity reactions 2

Important Monitoring

  • Assess for clinical improvement within 48-72 hours 3
  • If no improvement is seen within 48 hours or if clinical deterioration occurs, reevaluation is necessary 3

Prescription Format

Rx: Amoxicillin 400mg/5ml oral suspension Sig: Give 5.6ml by mouth twice daily for 10 days Disp: 120ml Refills: 0

References

Guideline

Amoxicillin Dosing Guidelines for Pediatric Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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