What can cause coughing, nausea, vomiting, and gastroesophageal reflux disease (GERD)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 25, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Coughing, Nausea, Vomiting, and Acid Reflux

  • Single Most Likely Diagnosis

    • Gastroesophageal Reflux Disease (GERD): This condition is characterized by the backflow of stomach acid into the esophagus, leading to symptoms such as coughing, nausea, vomiting, and acid reflux. The presence of multiple symptoms related to the gastrointestinal tract and respiratory system makes GERD a likely diagnosis.
  • Other Likely Diagnoses

    • Viral Gastroenteritis: Infections like the norovirus or rotavirus can cause nausea, vomiting, and sometimes coughing due to irritation of the throat from vomiting.
    • Pneumonia: Certain types of pneumonia, especially those caused by viral or atypical bacterial infections, can present with cough, nausea, and vomiting, especially if the infection leads to dehydration or if there's an associated gastrointestinal involvement.
    • Asthma or Chronic Obstructive Pulmonary Disease (COPD) Exacerbation: Both conditions can cause coughing and, in severe cases, lead to nausea and vomiting due to prolonged coughing spells or respiratory distress.
  • Do Not Miss Diagnoses

    • Pulmonary Embolism: Although less common, a pulmonary embolism can cause sudden onset of cough, nausea, and vomiting, along with other symptoms like chest pain and shortness of breath. It's critical to consider this diagnosis due to its high mortality rate if untreated.
    • Myocardial Infarction (Heart Attack): In some cases, especially in women or diabetic patients, a heart attack can present with atypical symptoms including nausea, vomiting, and coughing, rather than the classic chest pain.
    • Pneumothorax: A collapsed lung can cause sudden chest pain, cough, and in severe cases, lead to nausea and vomiting due to pain and respiratory distress.
  • Rare Diagnoses

    • Eosinophilic Esophagitis: A chronic immune system disease in which a type of white blood cell, the eosinophil, builds up in the esophagus in response to an allergen or irritant, leading to difficulty swallowing, nausea, and vomiting.
    • Cystic Fibrosis: A genetic disorder that can cause severe damage to the lungs, digestive system, and other organs in the body, leading to symptoms such as persistent cough, nausea, and vomiting due to malabsorption and respiratory complications.
    • Foreign Body Aspiration: Although more common in children, adults can also accidentally inhale objects, leading to coughing, nausea, and vomiting, especially if the object causes an obstruction or leads to an infection.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.