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Last updated: October 19, 2025View editorial policy

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Differential Diagnosis for Thumb Finger Tip Pain

  • Single most likely diagnosis
    • Trigger thumb or trigger finger: This condition is characterized by pain and stiffness in the thumb, especially when bending or straightening. It's a common condition that can cause finger tip pain due to the tendon's inability to glide smoothly.
  • Other Likely diagnoses
    • Arthritis (osteoarthritis or rheumatoid arthritis): These conditions can cause pain and stiffness in the joints, including the thumb. The pain may be localized to the finger tip.
    • Trauma or injury: A recent injury, such as a bruise, cut, or fracture, can cause pain in the thumb finger tip.
    • Neuroma: A neuroma is a benign growth of nerve tissue that can cause pain, numbness, or tingling in the affected area, including the thumb.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Infection (e.g., paronychia or felon): Infections in the finger can cause severe pain, redness, and swelling. If left untreated, they can lead to serious complications, such as abscesses or osteomyelitis.
    • Referred pain from the neck or shoulder: In some cases, pain in the thumb can be referred from the neck or shoulder due to nerve compression or other conditions. Missing this diagnosis could lead to delayed treatment of a more serious underlying condition.
  • Rare diagnoses
    • Tumors (e.g., glomus tumor): Although rare, tumors can cause pain and other symptoms in the thumb finger tip.
    • Raynaud's disease: This condition affects blood flow to the fingers and toes, causing pain, numbness, and discoloration. It can be triggered by cold temperatures or stress.
    • Complex regional pain syndrome (CRPS): A chronic pain condition that can cause severe, burning pain in the affected area, including the thumb.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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