Differential Diagnosis for Vomiting after Eating

• Single most likely diagnosis
  • Gastroesophageal reflux disease (GERD): This condition is characterized by the backflow of stomach acid into the esophagus, often triggered by eating, which can lead to vomiting.
• Other Likely diagnoses
  • Food poisoning: Consuming contaminated or spoiled food can cause vomiting shortly after eating.
  • Viral gastroenteritis: Infections like norovirus can cause vomiting after eating due to inflammation of the stomach and intestines.
  • Irritable bowel syndrome (IBS): Some individuals with IBS may experience vomiting after eating certain foods that trigger their symptoms.
  • Peptic ulcer disease: Ulcers in the stomach or duodenum can cause vomiting after eating, especially if the ulcer is irritated by food.
• Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
  • Appendicitis: Although less common, vomiting after eating can be a symptom of appendicitis, especially if the appendix is located near the stomach or intestines.
  • Intestinal obstruction: A blockage in the intestines can cause severe vomiting after eating, which is a medical emergency.
  • Pancreatitis: Inflammation of the pancreas can cause vomiting after eating, and if left untreated, can lead to severe complications.
  • Food allergy: A severe allergic reaction to food can cause vomiting, and in some cases, anaphylaxis, which is life-threatening.
• Rare diagnoses
  • Gastroparesis: A condition where the stomach muscles are weakened, leading to delayed emptying of food, which can cause vomiting after eating.
  • Cyclic vomiting syndrome: A rare disorder characterized by recurring episodes of severe vomiting, often triggered by eating.
  • Rumination syndrome: A condition where food is regurgitated and then chewed again, which can cause vomiting after eating.
  • Eosinophilic esophagitis: A rare inflammatory condition of the esophagus that can cause vomiting after eating, especially if certain foods trigger the inflammation.