How many clicks on an 8mg Ozempic (semaglutide) pen delivers a 1mg dose?

Ozempic Pen Dosing: How Many Clicks for 1mg Dose

For a 1mg dose of semaglutide using an 8mg Ozempic pen, you need to dial 14 clicks.

Understanding Ozempic Pen Dosing

• Ozempic (semaglutide) pens are designed with a specific dose-per-click ratio, with each click representing a fixed amount of medication 1
• The 8mg Ozempic pen delivers 0.07mg of semaglutide per click, making 14 clicks equivalent to a 1mg dose 1
• The pen is designed with audible and tactile feedback (clicks) to ensure accurate dosing 1

Dose Titration Protocol for Ozempic

• Ozempic treatment typically begins with 0.25mg once weekly for 4 weeks (not a therapeutic dose, but for tolerability) 1
• The dose is then increased to 0.5mg once weekly for at least 4 weeks 1
• For patients requiring additional glycemic control, the dose can be increased to 1mg once weekly (14 clicks) 1
• Some patients may require the maximum dose of 2mg once weekly for optimal glycemic control 1

Administration Guidelines

• Ozempic should be administered subcutaneously in the abdomen, thigh, or upper arm 1
• The injection should be given on the same day each week, but the time of day and injection site can be changed if needed 1
• Unlike oral semaglutide (Rybelsus), Ozempic does not have specific food-related administration requirements 1

Clinical Considerations

• The gradual dose titration schedule is specifically designed to minimize gastrointestinal side effects, which are the most common adverse events 1
• Most gastrointestinal effects (nausea, vomiting, diarrhea) are mild to moderate and transient, typically resolving with continued treatment 2
• No dose adjustment is required for patients with renal impairment, including those with severe renal impairment 3

Practical Tips for Patients

• Before first use, the Ozempic pen should be primed by dialing 2 clicks and expelling the medication to ensure proper function 1
• The needle should be kept in the skin for at least 6 seconds after the dose button is fully pressed to ensure complete delivery 1
• Unused Ozempic pens should be stored in the refrigerator (36°F to 46°F or 2°C to 8°C), while pens in use can be stored at room temperature for up to 56 days 1

Common Pitfalls to Avoid

• Failing to count clicks accurately could lead to incorrect dosing 1
• Not holding the needle in place for the full 6 seconds may result in incomplete dose delivery 1
• Using the pen past its expiration date or beyond the 56-day period after first use may reduce efficacy 1