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Differential Diagnosis for Upper Abdomen Swelling

Single Most Likely Diagnosis

  • Functional Dyspepsia: This condition is characterized by recurring symptoms of upper abdominal discomfort or pain, bloating, and early satiety, which can be exacerbated by eating. The symptoms described, such as upper abdomen swelling that worsens after eating and is accompanied by flatulence, align closely with functional dyspepsia, making it a plausible primary diagnosis.

Other Likely Diagnoses

  • Gastroesophageal Reflux Disease (GERD): Symptoms can include bloating, discomfort, and swelling in the upper abdomen, especially after eating, due to acid reflux.
  • Irritable Bowel Syndrome (IBS): Although IBS typically affects the lower abdomen, some individuals may experience upper abdominal symptoms, including bloating and discomfort, which can be worsened by eating.
  • Food Intolerance: Intolerance to certain foods (e.g., lactose, gluten) can lead to bloating, gas, and abdominal discomfort after eating.

Do Not Miss Diagnoses

  • Gastric Cancer: Although less common, gastric cancer can present with nonspecific symptoms such as abdominal discomfort, bloating, and early satiety, especially in older adults or those with risk factors.
  • Pancreatic Cancer: Abdominal bloating and discomfort, particularly after eating, can be symptoms of pancreatic cancer, which requires early detection for effective treatment.
  • Cholecystitis or Cholelithiasis: Inflammation of the gallbladder or gallstones can cause right upper quadrant abdominal pain, which may radiate and cause swelling, especially after fatty meals.

Rare Diagnoses

  • Celiac Disease: An autoimmune disorder that causes the immune system to react to gluten, leading to inflammation and damage in the small intestine, which can result in abdominal bloating and discomfort.
  • Gastroparesis: A condition where the stomach takes too long to empty its contents, leading to bloating, nausea, and discomfort, especially after eating.
  • Scleroderma: A chronic disease characterized by deposition of collagen, leading to hardening and tightening of skin and connective tissues, which can affect the digestive system and cause symptoms like bloating and abdominal discomfort.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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