Differential Diagnosis for Inflammation in Lower Buccal Sulcus
- Single most likely diagnosis
- Irritation from dentures or oral appliances: This is a common cause of inflammation in the lower buccal sulcus, especially if the denture or appliance is not properly fitted or if there is an overextension of the denture flange.
- Other Likely diagnoses
- Trauma: Accidental biting of the cheek or a sharp edge from a tooth can cause inflammation in the lower buccal sulcus.
- Infection: Bacterial or fungal infections, such as those caused by poor oral hygiene or immunocompromised states, can lead to inflammation in this area.
- Allergic reactions: Allergic contact stomatitis or cheilitis can cause inflammation in the lower buccal sulcus due to an allergic reaction to substances like metals, plastics, or certain foods.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Squamous cell carcinoma: Although rare, this type of cancer can present as a non-healing ulcer or area of inflammation in the lower buccal sulcus, making it crucial to rule out with a biopsy if the inflammation persists.
- Necrotizing sialometaplasia: A rare condition that can mimic malignancy, characterized by necrosis of the salivary gland tissue, which may present with inflammation and ulceration in the buccal sulcus.
- Rare diagnoses
- Pemphigus vulgaris: An autoimmune disease that can cause blistering and inflammation in the oral cavity, including the lower buccal sulcus.
- Lichen planus: A chronic inflammatory condition that can affect the mucous membranes inside the mouth, leading to inflammation and white patches in the lower buccal sulcus.
- Tuberculosis: In rare cases, tuberculosis can manifest orally, including in the lower buccal sulcus, especially in immunocompromised individuals.