From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Marijuana-related fungal pneumonia should be treated with antifungal medications such as voriconazole or amphotericin B, with therapy continuing for at least 6-12 weeks depending on clinical response, as recommended by recent studies 1. The diagnosis of fungal pneumonia related to marijuana use involves identifying the presence of fungi in the lungs, which can be done through various tests such as PCR analysis, serologic tests, and imaging findings 2, 3, 4.
Key Considerations
- The condition occurs because marijuana can harbor various fungi including Aspergillus, Mucor, and Cryptococcus, which when inhaled can cause infection, especially in those with weakened immune systems 5, 3.
- Symptoms include persistent cough, chest pain, shortness of breath, fever, and fatigue, and prompt medical attention is essential as delayed treatment can lead to severe complications or death 5, 2, 3, 4.
- Prevention is crucial and involves avoiding smoking moldy marijuana, using clean equipment, and considering vaporizers instead of smoking, with immunocompromised individuals being particularly cautious 5, 2, 3, 4.
Treatment Options
- For severe cases, treatment typically involves antifungal medications such as voriconazole (loading dose of 6 mg/kg IV every 12 hours for 1 day, followed by 4 mg/kg IV every 12 hours) or amphotericin B (0.5-1.5 mg/kg/day IV) 3, 4.
- For less severe cases, oral antifungals like itraconazole (200 mg twice daily) may be used 5, 2.
- Supportive care including oxygen therapy, bronchodilators, and sometimes corticosteroids may be necessary 2, 4.