From the FDA Drug Label
For anxiety, most patients require an initial dose of 2 mg/day to 3 mg/day given twice daily or three times daily. The recommended dose of lorazepam (Ativan) for anxiety is 2 mg/day to 3 mg/day given twice daily or three times daily.
- The dose may need to be adjusted based on patient response.
- For a CT scan, the dose is not explicitly stated, but based on the general anxiety dose, a single dose of 2 mg could be considered, however this is not directly stated in the label. 1
From the Research
For anxiety before a CT scan, a typical dose of lorazepam is 0.5 to 2 mg taken by mouth about 30-60 minutes before the procedure, as recommended by recent guidelines and studies 2. The specific dose depends on your age, weight, medical history, and severity of anxiety. Elderly patients or those with liver problems typically require lower doses, often starting at 0.5 mg. Lorazepam works by enhancing the effect of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits brain activity, helping to reduce anxiety. Be aware that lorazepam can cause drowsiness and impaired coordination, so you should arrange for someone to drive you home after the scan. Do not drink alcohol or take other sedatives while using lorazepam. This medication requires a prescription, so you'll need to consult with your doctor before the CT scan to determine if it's appropriate for you and to get the exact dosage for your situation.
Some key points to consider when using lorazepam for anxiety before a CT scan include:
- The medication should be taken 30-60 minutes before the procedure to allow for optimal absorption and effect
- The dose may need to be adjusted based on individual factors, such as age and medical history
- Lorazepam can cause side effects, such as drowsiness and impaired coordination, so it's essential to have someone drive you home after the scan
- The medication should not be taken with alcohol or other sedatives, as this can increase the risk of adverse effects
It's also important to note that anxiety before a CT scan is a common issue, and there are other interventions that can be used to reduce anxiety, such as information, psychological support, and anxiety reduction protocols, as discussed in studies 3 and 4. However, lorazepam remains a commonly used and effective medication for anxiety in this setting, as supported by recent studies 2 and 5.