Timing of Anterior and Posterior Fontanelle Closure
The anterior fontanelle typically closes between 9-18 months of age (average 9.7 months), while the posterior fontanelle closes much earlier, usually by 2-3 months of age. 1
Anterior Fontanelle
Normal Development Pattern
- The anterior fontanelle reaches its maximum size at approximately 1 month of age (average 2.2 cm) 2
- After 6 months of age, the anterior fontanelle size begins to progressively decrease 3
- Mean closure time is 9.7 ± 5.0 months, with slight gender differences (girls: 10.3 ± 4.7 months, boys: 9.2 ± 5.1 months) 1
- By 12 months, approximately 26.5% of anterior fontanelles are closed 2
- By 24 months, approximately 93% of anterior fontanelles are closed 2
Variability Factors
- There is significant normal variation in fontanelle size and closure timing among healthy infants 4, 1
- No significant differences in anterior fontanelle size have been observed between genders, despite boys having larger head circumferences 4
- Racial differences may exist in fontanelle sizes and closure patterns, with studies showing Nigerian infants having larger fontanelles at birth but earlier closure compared to Caucasian and Chinese populations 5
- Fontanelle size is not significantly correlated with weight, length, or head circumference measurements 2
Posterior Fontanelle
- The posterior fontanelle is significantly smaller than the anterior fontanelle at birth
- The posterior fontanelle typically closes much earlier than the anterior fontanelle, usually by 2-3 months of age
- Due to its early closure, the posterior fontanelle has less clinical significance for ongoing monitoring compared to the anterior fontanelle
Clinical Significance
- Ultrasonography through the anterior fontanelle provides an excellent window to examine the infant brain without radiation exposure 6
- Premature closure of the anterior fontanelle may warrant further evaluation including:
- Regular developmental surveillance is recommended for infants with premature anterior fontanelle closure 7
Measurement Techniques
- The traditional method measures the anterior-posterior diameter (length) and transverse diameter (width), with the average of these two measurements representing fontanelle size 3
- Oblique measurements have been shown to be equally accurate as the traditional method 1
- Children with fontanelles measuring above the 95th percentile should be monitored closely and investigated further for potentially associated diseases 1