What is the dose of Cofitinib (Tofacitinib) in children?

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Last updated: March 25, 2025View editorial policy

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From the Research

Tofacitinib is not approved for use in children, and its safety and efficacy in pediatric populations have not been established. The provided evidence does not discuss the use of Tofacitinib in children, but rather focuses on the risks associated with codeine use in pediatric populations 1, 2, 3, 4, 5.

Key Considerations

  • The evidence provided does not address the use of Tofacitinib in children, and therefore, it is not possible to recommend a dose for pediatric use.
  • Tofacitinib is a medication that is typically used to treat certain adult conditions, such as rheumatoid arthritis, and its use in children is not supported by the available evidence.
  • The safety and efficacy of Tofacitinib in pediatric populations have not been established, and its use in children may pose potential risks.

Recommendations

  • Tofacitinib should not be used in children due to the lack of safety and efficacy data.
  • Pediatric patients should be treated with alternative therapies that have established safety and efficacy profiles in children.
  • Healthcare providers should exercise caution when prescribing medications to children and carefully consider the potential risks and benefits of each treatment option.

References

Research

The Use of Codeine and Tramadol in the Pediatric Population-What is the Verdict Now?

Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners, 2019

Research

Pharmacist and Pediatrician Knowledge of Codeine Use in Children.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2018

Research

[Codeine--Restrictions on use for children and teenagers].

Deutsche medizinische Wochenschrift (1946), 2015

Research

Codeine versus placebo for chronic cough in children.

The Cochrane database of systematic reviews, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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