Differential Diagnosis for Diffuse Abdominal and Back Pain
Single Most Likely Diagnosis
- Chronic Kidney Disease (CKD) or Kidney Stones: Given the patient's history of diabetes, which is a risk factor for CKD, and the presence of elevated RBC, hemoglobin, and hematocrit, suggesting possible dehydration or polycythemia related to CKD. The absence of tenderness on exam does not rule out kidney stones, as they can cause severe pain without localized tenderness.
Other Likely Diagnoses
- Diabetic Ketoacidosis (DKA): Although the patient is on saxagliptin, a DPP-4 inhibitor, DKA can still occur, especially if there's an underlying infection (suggested by elevated WBC and neutrophil count). However, the absence of specific symptoms like hyperglycemia, ketosis, or acidosis in the provided information makes this less clear.
- Musculoskeletal Pain: Given the diffuse nature of the pain and the absence of specific abdominal or back tenderness, musculoskeletal pain, possibly related to overuse or strain, could be considered.
- Pancreatitis: Although less likely given the lack of specific symptoms like vomiting or radiating pain, pancreatitis can cause diffuse abdominal pain. The mildly elevated triglyceride could be a risk factor, but it's not significantly high.
Do Not Miss Diagnoses
- Abdominal Aortic Aneurysm (AAA): This is a critical diagnosis to consider in any male over 40 presenting with back or abdominal pain, especially given the elevated hematocrit which could indicate chronic blood loss or polycythemia. An AAA can be asymptomatic until it ruptures, making it a "do not miss" diagnosis.
- Infectious Processes (e.g., Pyelonephritis, Sepsis): The elevated WBC and neutrophil count suggest an infectious process. Given the patient's diabetes, which increases the risk of infections, and the absence of localized tenderness, an infectious process affecting the kidneys (pyelonephritis) or a systemic infection (sepsis) must be considered.
- Myocardial Infarction: Although less common, myocardial infarction can present with atypical symptoms, including abdominal or back pain, especially in diabetic patients who may have altered pain perception.
Rare Diagnoses
- Polycythemia Vera: The elevated hemoglobin and hematocrit could suggest polycythemia vera, a myeloproliferative disorder. However, this would be less likely without other supporting symptoms or findings.
- Amyloidosis: This condition can cause diffuse pain and is associated with various systemic symptoms. However, it's rare and would require specific diagnostic testing to confirm.
- Porphyria: Acute intermittent porphyria can cause severe abdominal and back pain without tenderness, but it's a rare condition and would require specific diagnostic tests to diagnose.