What is the treatment for Paronychia?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 21, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Treatment for Paronychia

The treatment for paronychia should follow a stepwise approach based on severity, with first-line management including antiseptic soaks, topical antimicrobials, and anti-inflammatory agents, while surgical drainage is reserved for cases with abscess formation. 1

Classification and Initial Assessment

  • Paronychia is classified as acute (sudden onset, often infectious) or chronic (lasting >6 weeks, typically irritant dermatitis) 2
  • Evaluate severity based on parameters including redness, edema, discharge, and granulation tissue 1
  • Check for presence of pus or abscess formation which would require drainage 1
  • Assess for predisposing factors such as ingrown toenail (onychocryptosis) 1

Conservative Management (First-Line)

For Acute Paronychia:

  • Implement antiseptic soaks with dilute vinegar (50:50 dilution) or povidone-iodine for 10-15 minutes twice daily 1, 2
  • Apply topical 2% povidone-iodine twice daily to the affected area 3, 1
  • Use mid to high potency topical steroid ointment to nail folds twice daily to reduce inflammation 1
  • Warm soaks with or without Burow solution or 1% acetic acid can help reduce inflammation 2

For Chronic Paronychia:

  • Apply high-potency topical corticosteroids alone or combined with topical antibiotics 3, 4
  • Regular application of emollients to cuticles and periungual tissues 3, 1
  • Topical calcineurin inhibitors may be beneficial in steroid-resistant cases 4

Antimicrobial Therapy

  • For moderate to severe infection, oral antibiotics should be selected based on likely pathogens 1, 5
  • If initial treatment with cephalexin fails, consider switching to sulfamethoxazole-trimethoprim (Bactrim) for broader coverage including MRSA 5
  • Be aware that secondary bacterial or mycological superinfections are present in up to 25% of paronychia cases 3, 5
  • Consider obtaining bacterial, viral, and fungal cultures in treatment-resistant cases 5

Surgical Interventions

  • For paronychia with abscess formation, drainage is mandatory 2, 6
  • Drainage options range from using a hypodermic needle to a wide incision with a scalpel 2
  • For paronychia with onychocryptosis (ingrown toenail), use techniques such as dental floss nail technique to separate the lateral nail edge from underlying tissue 1
  • Silver nitrate chemical cauterization for excessive granulation tissue 3, 1
  • In severe chronic cases, surgical options include en bloc excision of the proximal nail fold or eponychial marsupialization 4, 7

Special Considerations

  • For pyogenic granuloma formation, consider scoop shave removal with hyfrecation or silver nitrate application 1
  • For recurrent, severe, or treatment-refractory cases, consider intralesional triamcinolone acetonide 1
  • Topical timolol 0.5% gel twice daily under occlusion has shown benefit in some cases 3
  • Patients with chronic paronychia unresponsive to standard treatment should be investigated for unusual causes, such as malignancy 6

Prevention of Recurrence

  • Gentle nail care: trim nails straight across and not too short 3, 5
  • Avoid repeated friction, trauma, and excessive pressure 3
  • Wear comfortable well-fitting shoes and cotton socks 3
  • Use protective gloves during activities involving water or chemicals 1, 5
  • Patient education is paramount to reduce the recurrence of acute and chronic paronychia 2

Follow-up

  • Reassess after 2 weeks of treatment 3, 5
  • If no improvement is seen, consider referral to dermatology or podiatry for further evaluation 1, 5
  • Treatment of chronic paronychia may take weeks to months for complete resolution 4

References

Guideline

Management of Paronychia of the Toenail

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Acute and Chronic Paronychia.

American family physician, 2017

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Management of chronic paronychia.

Indian journal of dermatology, 2014

Guideline

Management of Paronychia Not Responding to Cephalexin

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Toenail paronychia.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, 2016

Research

Swiss roll technique for treatment of paronychia.

Techniques in hand & upper extremity surgery, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.