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Differential Diagnosis for Resolving Rash with Residual Redness on Palms

  • Single most likely diagnosis
    • Contact Dermatitis: This is a common condition that can cause a rash on the palms, especially if the individual has been exposed to an allergen or irritant. The residual redness along the perimeters of the palms could be a sign of the rash resolving.
  • Other Likely diagnoses
    • Dyshidrotic Eczema: A type of eczema that typically affects the palms and soles, characterized by small, itchy blisters. As it resolves, it may leave behind redness.
    • Psoriasis: Palmar psoriasis can cause red, scaly patches on the palms. The residual redness could be a sign of the condition resolving or partially treated.
    • Pompholyx: Similar to dyshidrotic eczema, it causes blisters on the palms and soles, which can leave redness as they resolve.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Secondary Syphilis: Can cause a rash on the palms and soles, which is a critical diagnosis to consider due to the potential for serious complications if left untreated.
    • Lyme Disease: Although less common, Lyme disease can cause a rash that might resemble the described symptoms, and missing this diagnosis could lead to severe health issues.
  • Rare diagnoses
    • Keratoderma Blennorrhagicum: A rare condition associated with Reiter's syndrome, characterized by a rash on the palms and soles.
    • Pityriasis Rubra Pilaris: A rare skin disorder that can cause a rash and redness on various parts of the body, including the palms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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