Treatment of Tension Headaches
For acute treatment of tension headaches, ibuprofen 400 mg or acetaminophen 1000 mg are recommended as first-line options. 1, 2
Acute Treatment
- Ibuprofen 400 mg is recommended for the short-term treatment of tension-type headache, showing significant improvement in pain-free response at 2 hours 1, 2
- Acetaminophen 1000 mg is an equally effective alternative for acute treatment of tension headaches 1, 2, 3
- Medications should be taken early in the headache episode for maximum effectiveness 2
- For severe attacks with nausea, consider adding an antiemetic medication to improve treatment outcomes 2
- If inadequate response to initial treatment, consider combination therapy with caffeine-containing preparations or try alternative NSAIDs such as naproxen sodium 2, 4
Preventive Treatment
- Amitriptyline is recommended for prevention of chronic tension-type headache 1, 2
- Starting doses of amitriptyline typically range from 10-25 mg at bedtime, with gradual titration up to 50-100 mg as needed and tolerated 2, 5
- Preventive treatment should be considered when:
Medication Overuse Considerations
- Limit use of acute headache medications to no more than 2 days per week to prevent medication overuse headache 2, 6
- If medication overuse is present, gradual withdrawal of the overused medication is necessary 1
- Non-opioids and triptans may be stopped abruptly or weaned down within a month 1
- Opioid medications should be gradually removed over a longer period 1
Non-Pharmacological Approaches
- Physical therapy and aerobic exercise are recommended as adjunctive management options 2
- Lifestyle modifications should include:
- Regular meals and adequate hydration
- Sleep hygiene improvement
- Stress management techniques 1
- Behavioral interventions such as biofeedback, relaxation training, and cognitive therapy may be beneficial 6
- Some evidence supports osteopathic manipulative treatment for tension headaches not responsive to medication 7
Treatment Algorithm
- First step: For acute episodes, use ibuprofen 400 mg or acetaminophen 1000 mg at onset of headache 1, 2
- If inadequate relief: Consider combination analgesics with caffeine or try alternative NSAIDs 2
- For chronic tension headaches (frequent episodes):
- Incorporate non-pharmacological approaches alongside medication treatment 2, 7
Cautions and Monitoring
- Avoid opioids for tension-type headache due to risk of dependence and medication overuse headache 2
- Monitor for medication overuse (use of acute treatments >2 days/week) 2
- Be aware of anticholinergic adverse effects with amitriptyline, especially in older patients and those with cardiac comorbidities 2
- Regularly assess treatment effectiveness and adjust therapy as needed 2