What is the treatment for tension headaches?

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Treatment of Tension Headaches

For acute treatment of tension headaches, ibuprofen 400 mg or acetaminophen 1000 mg are recommended as first-line options. 1, 2

Acute Treatment

  • Ibuprofen 400 mg is recommended for the short-term treatment of tension-type headache, showing significant improvement in pain-free response at 2 hours 1, 2
  • Acetaminophen 1000 mg is an equally effective alternative for acute treatment of tension headaches 1, 2, 3
  • Medications should be taken early in the headache episode for maximum effectiveness 2
  • For severe attacks with nausea, consider adding an antiemetic medication to improve treatment outcomes 2
  • If inadequate response to initial treatment, consider combination therapy with caffeine-containing preparations or try alternative NSAIDs such as naproxen sodium 2, 4

Preventive Treatment

  • Amitriptyline is recommended for prevention of chronic tension-type headache 1, 2
  • Starting doses of amitriptyline typically range from 10-25 mg at bedtime, with gradual titration up to 50-100 mg as needed and tolerated 2, 5
  • Preventive treatment should be considered when:
    • Headaches occur frequently (more than 2 days per week)
    • Acute medications are being used more than twice weekly (risk of medication overuse headache) 2, 6
    • Headaches significantly impact quality of life 2

Medication Overuse Considerations

  • Limit use of acute headache medications to no more than 2 days per week to prevent medication overuse headache 2, 6
  • If medication overuse is present, gradual withdrawal of the overused medication is necessary 1
  • Non-opioids and triptans may be stopped abruptly or weaned down within a month 1
  • Opioid medications should be gradually removed over a longer period 1

Non-Pharmacological Approaches

  • Physical therapy and aerobic exercise are recommended as adjunctive management options 2
  • Lifestyle modifications should include:
    • Regular meals and adequate hydration
    • Sleep hygiene improvement
    • Stress management techniques 1
  • Behavioral interventions such as biofeedback, relaxation training, and cognitive therapy may be beneficial 6
  • Some evidence supports osteopathic manipulative treatment for tension headaches not responsive to medication 7

Treatment Algorithm

  1. First step: For acute episodes, use ibuprofen 400 mg or acetaminophen 1000 mg at onset of headache 1, 2
  2. If inadequate relief: Consider combination analgesics with caffeine or try alternative NSAIDs 2
  3. For chronic tension headaches (frequent episodes):
    • Start amitriptyline at low dose (10-25 mg) at bedtime 2
    • Gradually increase to effective dose (typically 50-100 mg) 2, 5
    • Monitor for anticholinergic side effects (dry mouth, constipation, urinary retention, blurred vision) 2
  4. Incorporate non-pharmacological approaches alongside medication treatment 2, 7

Cautions and Monitoring

  • Avoid opioids for tension-type headache due to risk of dependence and medication overuse headache 2
  • Monitor for medication overuse (use of acute treatments >2 days/week) 2
  • Be aware of anticholinergic adverse effects with amitriptyline, especially in older patients and those with cardiac comorbidities 2
  • Regularly assess treatment effectiveness and adjust therapy as needed 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment of Tension Type Headache

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Tension-type headache.

American family physician, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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