What are the treatment options for shoulder pain?

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Last updated: October 22, 2025View editorial policy

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Treatment Options for Shoulder Pain

The most effective treatment for shoulder pain includes a combination of physical therapy, medication, and interventions targeting specific underlying causes, with treatment selection based on the etiology of pain.

Initial Assessment and Diagnosis

  • Radiography is the preferred initial imaging study for traumatic shoulder pain, with standard views including anteroposterior views in internal and external rotation and an axillary or scapula-Y view 1
  • Clinical assessment should include musculoskeletal evaluation, evaluation of spasticity, identification of any subluxation, and testing for regional sensory changes 1
  • Ultrasound may be considered as a diagnostic tool for shoulder soft tissue injury 1

Conservative Management

Physical Therapy

  • Range of motion exercises focusing especially on external rotation and abduction are recommended to prevent frozen shoulder and shoulder-hand-pain syndrome 1
  • Avoid overhead pulley exercises, which encourage uncontrolled abduction and can increase the incidence of developing hemiplegic shoulder pain 1
  • Rotator cuff strengthening exercises are recommended to protect the glenohumeral joint 2

Medications

  • Non-steroidal anti-inflammatory drugs are recommended as first-line pharmacological therapy for reduction of pain and inflammation 2
  • Supplementation of oral vitamin C and vitamin D can help slow down cartilage degeneration in osteoarthritic conditions 2
  • Neuromodulating medications may be considered for patients with central pain components associated with sensory changes, allodynia, and hyperpathia 1, 3

Interventional Treatments

Injections

  • Intra-articular corticosteroid injections (Triamcinolone) have been found to have significant effects on pain reduction 1
  • Suprascapular nerve blocks are effective in reducing shoulder pain through reduction of both nociceptive and neuropathic pain mechanisms for up to 12 weeks 1, 3
  • Botulinum toxin injections can be useful to reduce severe hypertonicity in shoulder muscles and may decrease pain associated with spasticity-related joint mobility restrictions 1, 3

Electrical Stimulation

  • Functional electrical stimulation (FES) may be considered for shoulder pain and has been shown to improve shoulder lateral rotation 1
  • Neuromuscular electrical stimulation (NMES) may be considered (surface or intramuscular) for shoulder pain 1

Supportive Measures

  • Shoulder strapping (sling) is recommended to prevent shoulder pain in the involved upper extremity 1
  • Positioning and use of supportive devices are reasonable to consider for shoulder subluxation 1
  • Modalities including ice, heat, and soft tissue massage can be used to reduce pain/swelling and improve circulation, tissue elasticity, and range of motion 1

Surgical Options

  • Surgical tenotomy of pectoralis major, lattisimus dorsi, teres major, or subscapularis may be considered for patients with severe hemiplegia and restrictions in shoulder range of motion 1
  • Most soft-tissue injuries (such as labral tears and rotator cuff tears) can undergo a period of conservative management before considering surgery 1, 4
  • Surgical interventions are typically considered when symptoms persist or worsen after 6-12 weeks of directed conservative treatment 5

Treatment Algorithm Based on Etiology

For Hemiplegic Shoulder Pain

  1. First-line: Patient education on positioning and range of motion exercises 1, 3
  2. Second-line: Electrical stimulation and shoulder strapping 1
  3. Third-line: Intra-articular injections (Triamcinolone) or suprascapular nerve blocks 1
  4. Fourth-line: Botulinum toxin injections for spasticity-related pain 1, 3
  5. Fifth-line: Surgical tenotomy for severe cases with restricted motion 1

For Inflammatory/Structural Shoulder Pain

  1. First-line: NSAIDs and physical therapy focusing on ROM and strengthening 2, 5
  2. Second-line: Corticosteroid injections (subacromial or glenohumeral) 1, 5
  3. Third-line: Suprascapular nerve blocks 3
  4. Fourth-line: Referral for surgical evaluation if no improvement after 3-6 months 4, 5

Common Pitfalls and Caveats

  • Overhead pulley exercises should be avoided as they can worsen shoulder pain 1
  • Corticosteroid injections provide only short-term relief and long-term pain reduction has not been verified 3
  • Biologics such as platelet-rich plasma may help decrease shoulder pain but neither stop progression nor improve osteoarthritis 2
  • The effectiveness of acupuncture as an adjuvant treatment for hemiplegic shoulder pain remains uncertain 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Non-operative management of shoulder osteoarthritis: Current concepts.

Journal of ISAKOS : joint disorders & orthopaedic sports medicine, 2023

Guideline

Management of Shoulder Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Surgical options for patients with shoulder pain.

Nature reviews. Rheumatology, 2010

Research

Chronic shoulder pain: part II. Treatment.

American family physician, 2008

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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