What is the workup for postoperative C5 palsy (cervical spine nerve root injury) after posterior cervical spine decompression?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 25, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

The workup for postoperative C5 palsy after posterior cervical spine decompression should begin with immediate neurological assessment to document the extent of the deficit, typically manifesting as deltoid and/or biceps weakness. Obtain urgent cervical spine MRI to rule out hematoma, inadequate decompression, or new compression, as suggested by 1. Electromyography (EMG) and nerve conduction studies should be performed 3-4 weeks after onset to confirm the diagnosis and assess severity. Laboratory tests including complete blood count, inflammatory markers, and electrolytes help exclude systemic causes. Management typically involves physical therapy focusing on range of motion and strengthening exercises, starting with 3-5 sessions weekly for 6-8 weeks. Pain control with NSAIDs like ibuprofen 400-600mg every 6 hours or acetaminophen 500-1000mg every 6 hours may be needed. Most cases resolve spontaneously within 3-6 months with conservative management. C5 palsy occurs in 4-11% of posterior cervical decompressions due to nerve root tethering during cord shift, direct nerve injury, or reperfusion injury to the nerve root, as reported by 2. Close monitoring with follow-up neurological examinations at 2 weeks, 6 weeks, 3 months, and 6 months post-diagnosis is recommended to track recovery progress. Risk factors for C5 palsy include ossification of the posterior longitudinal ligament, narrower intervertebral foramen, laminectomy, excessive spinal cord drift, and male gender, as identified by 3. Preventive measures such as foraminotomy and intraoperative neuromonitoring may be considered, especially in high-risk patients, as suggested by 4 and 2. Overall, a comprehensive approach to diagnosis and management is crucial to optimize outcomes in patients with postoperative C5 palsy.

References

Research

C5 nerve root palsy after posterior cervical spine surgery.

Journal of orthopaedic surgery (Hong Kong), 2017

Research

C5 nerve root palsy following decompression of cervical spine with anterior versus posterior types of procedures in patients with cervical myelopathy.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.