What is the recommended treatment for a patient with severe osteoarthritis and a nonunion nondisplaced intra-articular proximal phalanx great toe fracture?

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Management of Severe Osteoarthritis with Nonunion Nondisplaced Intra-articular Proximal Phalanx Great Toe Fracture

For a patient with severe osteoarthritis and a nonunion nondisplaced intra-articular proximal phalanx great toe fracture, joint replacement surgery is the recommended treatment when conservative measures have failed to provide adequate pain relief and functional improvement. 1

Initial Conservative Management

  • Begin with core treatments for osteoarthritis including:

    • Education about the condition and self-management strategies 2
    • Activity modification to reduce mechanical stress on the affected joint 2
    • Exercise regimens for range of motion and strengthening 2
    • Weight loss if the patient is overweight or obese 2
  • First-line pharmacological management:

    • Regular paracetamol (acetaminophen) for pain relief 2
    • Topical NSAIDs before considering oral medications 2
    • Topical capsaicin as an adjunct for pain relief 2
  • Second-line pharmacological options if first-line treatments are insufficient:

    • Oral NSAIDs at the lowest effective dose for the shortest possible period 2
    • COX-2 inhibitors with a proton pump inhibitor in patients with gastrointestinal risk factors 2
    • Opioid analgesics may be considered for short-term use when other options fail 2
  • Consider intra-articular corticosteroid injections for moderate to severe pain 2

Surgical Management for Nonunion Fracture with Severe OA

  • Surgical intervention is indicated when:

    • Conservative treatments have failed 1
    • The patient has marked pain and/or disability 1
    • Functional limitation is severe 2
  • Surgical options for the great toe with both severe OA and nonunion fracture:

    • Arthrodesis (joint fusion) is the preferred option for intra-articular fractures with concurrent severe osteoarthritis 1, 3
    • Trapeziectomy may be considered for thumb base OA but is less applicable to the great toe 2, 1
    • Arthroplasty (joint replacement) can be considered in selected cases 2, 1
  • For the specific case of nonunion intra-articular fracture:

    • Open reduction and internal fixation with bone grafting may be necessary to address the nonunion before or during the definitive procedure 4, 5
    • Intra-articular osteotomy may be considered if the fracture has malunited rather than non-united 4

Important Considerations and Potential Complications

  • High complication rates have been reported with surgical intervention for intra-articular fractures of the great toe 3

    • Potential complications include redisplacement, painful nonunion, refracture, posttraumatic arthritis, avascular necrosis, and hardware migration 3
  • Patient-specific factors such as age, sex, smoking, obesity, and comorbidities should not be barriers to referral for joint replacement surgery 2

  • For nonunion fractures specifically, newer techniques such as extracorporeal shock wave therapy combined with platelet-rich plasma injections have shown promise in case reports but lack robust evidence for routine use 6

  • Postoperative rehabilitation is essential to maximize functional outcomes and should include:

    • Progressive range of motion exercises 2
    • Strengthening exercises 2
    • Gait training with appropriate assistive devices if needed 2

Follow-up Care

  • Long-term follow-up should be adapted to the patient's individual needs 2
  • Regular monitoring for complications and assessment of functional outcomes is essential 2
  • Continued pain management may be necessary during the recovery period 2

References

Guideline

Surgical Management of Thumb Arthritis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Nonunion in proximal phalanx of great toe treated by grafting with precisely processed autologous bone PEG.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, 2011

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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