What are the steps to set up a Nexplanon (etonogestrel implant) tray for insertion?

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Last updated: October 22, 2025View editorial policy

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Setting Up a Nexplanon Tray for Insertion

To properly set up a Nexplanon (etonogestrel implant) tray for insertion, follow these specific steps to ensure a safe and effective procedure.

Preparation of Materials

  • Verify that you have the Nexplanon applicator package containing the sterile disposable applicator preloaded with the single implant 1
  • Ensure the following additional items are available:
    • Clean examination table for the patient to lie on 2
    • Sterile surgical drapes to create a sterile field 2
    • Sterile gloves for the provider 2
    • Antiseptic solution (such as chlorhexidine) for skin preparation 2
    • Local anesthetic (1-2% lidocaine with or without epinephrine) 1
    • Sterile gauze 2
    • Sterile adhesive bandage and pressure bandage 2
    • Surgical marker to mark insertion site 2

Anatomical Considerations for Safe Insertion

  • Identify the proper insertion site on the inner side of the non-dominant upper arm about 8-10 cm above the medial epicondyle of the humerus 3
  • Avoid insertion near the sulcus (groove) between the biceps and triceps muscles to prevent nerve injury 3
  • Mark the insertion site and the path of insertion with a surgical marker 2
  • Position the patient's arm with elbow flexed and hand positioned under the head (or as directed in current insertion instructions) 2

Procedural Setup

  • Open the sterile package containing the Nexplanon applicator only when ready to perform the insertion 2
  • Verify the presence of the implant in the needle by looking at the transparent chamber of the applicator 2
  • Prepare the insertion site using antiseptic solution in a circular motion for at least 30 seconds 2
  • Draw up local anesthetic in a syringe with a small gauge needle for administration at the insertion site 1

Critical Safety Considerations

  • Always complete the Nexplanon clinical training program before attempting insertion 1, 2
  • Be familiar with the proper insertion technique to avoid complications such as deep insertion or nerve injury 3
  • Understand that incorrect insertion (non-insertion, partial insertion, or deep insertion) occurs at a rate of approximately 12.6 per 1000 insertions 2
  • Be aware of the potential for rare complications such as nerve injury, which can cause forearm pain and hypoesthesia 3

Post-Insertion Setup

  • Prepare a pressure bandage to apply over the insertion site after the procedure 2
  • Have patient education materials ready regarding expected side effects, particularly changes in menstrual bleeding patterns 1
  • Document the procedure, including lot number and expiration date of the implant 2

Common Pitfalls to Avoid

  • Failure to properly identify anatomical landmarks can lead to nerve injury or deep insertion 3
  • Incorrect insertion technique may result in non-insertion, partial insertion, or deep insertion 2
  • Improper sterile technique can lead to infection at the insertion site 2
  • Insertion too deep can make removal difficult due to encasement of the implant in fibrotic tissue 2

Remember that proper training is essential before performing Nexplanon insertions, and all healthcare providers must complete the required clinical training program to minimize procedure-related complications 1, 2.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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