Differential Diagnosis for Burning Sensation
- Single most likely diagnosis
- Gastroesophageal reflux disease (GERD): This is often the most common cause of a burning sensation, especially in the chest or throat area, due to the reflux of stomach acid into the esophagus.
- Other Likely diagnoses
- Peptic ulcer disease: Ulcers in the stomach or duodenum can cause a burning pain, typically in the upper abdomen.
- Esophagitis: Inflammation of the esophagus, which can be caused by acid reflux, infections, or other irritants, leading to a burning sensation.
- Gastritis: Inflammation of the stomach lining, which can cause burning pain or discomfort in the upper abdomen.
- Dyspepsia: A term for indigestion or an upset stomach, which can include a burning sensation, often related to eating.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Myocardial infarction (heart attack): Although less common, a burning sensation in the chest can be a symptom of a heart attack, especially if accompanied by other symptoms like shortness of breath, arm pain, or jaw pain.
- Pulmonary embolism: A blockage in one of the arteries in the lungs, which can cause sudden and severe burning chest pain, among other symptoms.
- Esophageal rupture or perforation: A serious condition where the esophagus tears, which can cause severe chest pain and burning sensation.
- Rare diagnoses
- Zollinger-Ellison syndrome: A rare disorder characterized by excessive production of stomach acid, leading to severe ulcers and burning pain.
- Eosinophilic esophagitis: A chronic immune system disease in which a type of white blood cell, the eosinophil, builds up in the esophagus in response to an allergen or irritant, causing inflammation and burning sensation.
- Certain infections (e.g., esophageal candidiasis): Fungal infections of the esophagus can cause burning pain, especially in immunocompromised individuals.