Differential Diagnosis for Easy Bruising in a 44-year-old Female
Single Most Likely Diagnosis
- Vitamin C deficiency: Easy bruising can be a symptom of vitamin C deficiency, which is relatively common and can be caused by a poor diet or increased requirement for the vitamin.
Other Likely Diagnoses
- Idiopathic thrombocytopenic purpura (ITP): An autoimmune condition characterized by low platelet count, leading to easy bruising and bleeding.
- Medication side effects (e.g., anticoagulants, aspirin, NSAIDs): Certain medications can interfere with blood clotting, leading to easy bruising.
- Hormonal changes (e.g., menopause, pregnancy): Hormonal fluctuations can affect blood vessels and lead to easy bruising.
- Vitamin K deficiency: Vitamin K plays a crucial role in blood clotting, and its deficiency can cause easy bruising.
Do Not Miss Diagnoses
- Leukemia: Certain types of leukemia can cause easy bruising due to bone marrow suppression and decreased platelet production.
- Liver disease (e.g., cirrhosis): Liver disease can lead to coagulopathy and easy bruising.
- Bleeding disorders (e.g., hemophilia, von Willebrand disease): These conditions can cause easy bruising and bleeding due to defects in blood clotting factors.
- Bone marrow failure (e.g., aplastic anemia): Bone marrow failure can lead to decreased production of blood cells, including platelets, causing easy bruising.
Rare Diagnoses
- Ehlers-Danlos syndrome: A genetic disorder that affects connective tissue, leading to fragile blood vessels and easy bruising.
- Pseudoxanthoma elasticum: A rare genetic disorder that affects the skin, eyes, and cardiovascular system, causing easy bruising and bleeding.
- Scurvy: A rare condition caused by severe vitamin C deficiency, leading to easy bruising, bleeding, and other symptoms.