Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 18 yo Male with Stomach Pain and Depression

  • Single most likely diagnosis:
    • Peptic Ulcer Disease: The patient's symptoms of stomach pain, occasional guarding, and bending over suggest abdominal pain that could be related to peptic ulcer disease, especially given the association with stress and potentially decreased eating, which can exacerbate symptoms. The feeling of depression could be a contributing factor or a result of chronic pain.
  • Other Likely diagnoses:
    • Gastroesophageal Reflux Disease (GERD): This condition could cause stomach pain and discomfort, especially after eating or at night, and might be exacerbated by stress or changes in eating habits.
    • Irritable Bowel Syndrome (IBS): Although IBS typically presents with a mix of abdominal pain and changes in bowel habits, the abdominal pain and occasional guarding could fit, especially if the patient has not mentioned specific bowel changes.
    • Stress-induced gastritis: Given the patient's depression and potential stress, this could lead to inflammation of the stomach lining, causing pain.
  • Do Not Miss diagnoses:
    • Appendicitis: Although the patient's symptoms do not perfectly align with classic appendicitis (e.g., pain typically starts around the navel and then moves to the lower right abdomen), appendicitis can present atypically, especially in younger patients, and is a surgical emergency.
    • Pancreatitis: This condition can cause severe abdominal pain and could be related to gallstones, alcohol use, or other causes. It's crucial to consider, especially if the patient has risk factors.
    • Intestinal obstruction: This is a condition where the intestine is partially or completely blocked, which can cause severe abdominal pain, vomiting, and constipation. It requires immediate medical attention.
  • Rare diagnoses:
    • Inflammatory bowel disease (Crohn's disease or ulcerative colitis): These conditions can cause chronic abdominal pain, changes in bowel habits, and sometimes depression due to chronic illness.
    • Gastric cancer: Although extremely rare in an 18-year-old, it's a consideration in the differential diagnosis of stomach pain, especially if there's a family history or other risk factors.
    • Porphyrias: A group of rare disorders that can cause abdominal pain, neurological symptoms, and sometimes psychiatric symptoms like depression.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.