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Differential Diagnosis for a Large Rubbery Mass in the Right Lower Quadrant (RLQ)

Single Most Likely Diagnosis

  • Ovarian cyst or tumor: Given the description of a large rubbery mass in the RLQ, which is a common location for ovarian pathology, an ovarian cyst or tumor is a highly plausible diagnosis. The dull pain associated with it also aligns with symptoms often reported by patients with ovarian masses.

Other Likely Diagnoses

  • Uterine fibroid: Although less common in the RLQ, a large uterine fibroid could potentially present in this manner, especially if the fibroid is pedunculated and has torsioned or is located in a position that refers pain to the RLQ.
  • Intestinal or mesenteric cyst: These can present as large, rubbery masses and could cause dull pain, depending on their size and location.
  • Lymphoma or other lymphoproliferative disorders: Enlarged lymph nodes in the mesentery or retroperitoneum could present as a large mass in the RLQ, though they might not typically be described as "rubbery."

Do Not Miss Diagnoses

  • Appendiceal mass or abscess: Although the pain is described as dull and 4/10, which is not typical for acute appendicitis, an appendiceal mass or abscess could present with a palpable mass in the RLQ and should not be missed due to the potential for serious complications if not treated promptly.
  • Ectopic pregnancy: In women of childbearing age, ectopic pregnancy is a critical diagnosis to consider, even though the presentation might not be typical. A large mass could potentially be a ruptured ectopic pregnancy, which is a medical emergency.
  • Torsion of an ovarian cyst or tumor: This condition can lead to severe pain and is an emergency. The initial presentation might be less severe, making it crucial not to miss this diagnosis.

Rare Diagnoses

  • Retroperitoneal sarcoma: These are rare tumors that can present as large masses in the retroperitoneum, including the RLQ.
  • Gastrointestinal stromal tumor (GIST): Although more commonly found in the stomach, GISTs can occur in the small intestine and present as a mass in the RLQ.
  • Desmoid tumor: A type of benign tumor that can occur in the abdominal wall or intra-abdominally, potentially presenting as a large, firm mass.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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