What are the causes of neutrophilia?

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From the Research

Causes of Neutrophilia

The causes of neutrophilia can be categorized into several groups, including:

  • Infection: Neutrophilia can occur in response to bacterial or fungal infections 1, 2
  • Inflammatory conditions: Conditions such as rheumatoid arthritis and systemic lupus erythematosus can cause neutrophilia 3
  • Myeloproliferative disorders: Disorders that affect the production of blood cells in the bone marrow can lead to neutrophilia 1
  • Malignancies: Certain types of cancer can cause neutrophilia 1, 2
  • Endocrinopathies: Hormonal disorders can affect the production of neutrophils 1
  • Drugs: Certain medications can cause neutrophilia as a side effect 1
  • Anemia: A decrease in red blood cells can lead to an increase in neutrophils 1
  • Rare disorders: Conditions such as leukocyte adhesion deficiency can cause neutrophilia 1
  • Other factors: Stress, exercise, smoking, obesity, and obstructive sleep apnea have been associated with chronic idiopathic neutrophilia (CIN) 1

Specific Conditions

Certain conditions can cause neutrophilia, including:

  • Systemic autoimmune diseases: Neutrophils play a role in the pathogenesis of these conditions 3
  • Cardiovascular disease: Neutrophils can contribute to the development of cardiovascular disease 2
  • Cancer: Neutrophils can promote or aggravate cancer development 2

References

2
Research

Neutrophils in Physiology and Pathology.

Annual review of pathology, 2024

3
Research

Role of neutrophils in systemic autoimmune diseases.

Arthritis research & therapy, 2013

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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