Differential Diagnosis for Photophobia, Ocular Pain with Movement, Fever, No Headache, Normal Neurological Exam, CBC Normal

• Single Most Likely Diagnosis
  • Viral Conjunctivitis: This condition is characterized by inflammation of the conjunctiva, often presenting with photophobia, ocular pain (especially with movement), and fever. The absence of headache and a normal neurological exam, along with a normal CBC, supports this diagnosis as it typically doesn't affect the CBC results or neurological status.
• Other Likely Diagnoses
  • Bacterial Conjunctivitis: Similar to viral conjunctivitis but often with a more purulent discharge. It could present with photophobia and ocular pain, especially with movement, and fever.
  • Uveitis: Inflammation of the uvea, which can cause photophobia, pain (especially with movement), and fever. It might not directly cause an abnormal CBC, but the presence of fever and ocular symptoms could align with this diagnosis.
• Do Not Miss Diagnoses
  • Endophthalmitis: A severe, vision-threatening infection within the eye. Although less common, it's critical to consider due to its potential for severe consequences, including vision loss. Symptoms can include severe ocular pain, photophobia, and fever.
  • Orbital Cellulitis: An infection of the tissues surrounding the eye, which can cause pain with eye movement, fever, and photophobia. It's a serious condition that requires prompt treatment to prevent complications.
• Rare Diagnoses
  • Sarcoidosis: A systemic disease that can cause uveitis, leading to photophobia and ocular pain. It's less common but should be considered in the differential, especially if other systemic symptoms are present.
  • Syphilis (Secondary): Can cause a variety of ocular symptoms, including uveitis and conjunctivitis, leading to photophobia and pain. Although rare, it's an important consideration due to its systemic implications and the need for specific treatment.