Neurological Examination Protocol
The proper procedure for conducting a neurological examination includes systematic assessment of level of consciousness, cranial nerves, motor function, sensory function, coordination, and reflexes, following standardized protocols to ensure comprehensive evaluation of neurological status. 1, 2
Level of Consciousness Assessment
- Assess alertness using the Glasgow Coma Scale (GCS) components: eye opening, verbal response, and motor response 3
- Evaluate orientation by asking patients about person, place, and time 2
- Test ability to follow commands by asking patients to open/close eyes and grip/release hand 2
- Document the ICE (Immune Effector Cell-Associated Encephalopathy) score in patients receiving immunotherapy to track neurological status 3
Cranial Nerve Assessment
- Test all 12 cranial nerves systematically: 1, 2
- CN I: Assess smell (optional in routine examination)
- CN II: Check visual acuity and visual fields using confrontation testing
- CN III, IV, VI: Evaluate pupillary size, reactivity, and eye movements
- CN V: Test facial sensation in all three divisions and jaw strength
- CN VII: Assess facial symmetry and movement
- CN VIII: Evaluate hearing
- CN IX, X: Check gag reflex, voice quality, and swallowing
- CN XI: Test shoulder shrug and head turning strength
- CN XII: Observe tongue movement and symmetry
Motor Function Assessment
- Have patients extend arms at 90° (seated) or 45° (supine) for 10 seconds to detect drift 2
- Ask patients to raise legs 30° and hold for 5 seconds 2
- Assess strength in major muscle groups using the 0-5 scale 2
- Evaluate muscle tone through passive range of motion 2
- Check for abnormal movements such as tremor, myoclonus, or asterixis 3
Sensory Function Assessment
- Test various sensory modalities including: 1, 2
- Light touch
- Pain/temperature sensation using pinprick
- Vibration using a tuning fork
- Proprioception (joint position sense)
- Compare symmetry between sides 2
Coordination and Cerebellar Function
- Test finger-to-nose and heel-to-shin movements to detect ataxia 2
- Assess rapid alternating movements 1
- Evaluate gait and balance if patient is able to stand and walk 3
Reflex Testing
- Check deep tendon reflexes (biceps, triceps, brachioradialis, patellar, Achilles) 2
- Test for pathological reflexes including Babinski sign 2
- Assess for frontal release signs in patients with suspected cognitive impairment 4
Cognitive Assessment
- Evaluate language function through naming objects, repetition, and comprehension 2
- Test memory (immediate, recent, and remote) 4
- Assess attention and concentration 4
- Screen for neglect or inattention using simultaneous bilateral stimulation 2
Documentation and Standardized Scales
- Use the NIH Stroke Scale (NIHSS) for patients with suspected stroke 3
- Apply the Glasgow Coma Scale for trauma patients or altered consciousness 3
- Document baseline status and any changes over time 1
- Consider using standardized cognitive assessment tools like Mini-Mental State Examination or Montreal Cognitive Assessment when appropriate 5, 4
Special Considerations
- Perform more frequent assessments (every 1-4 hours) in critically ill patients 1
- Note medications that may affect the neurological assessment, such as sedatives 2
- Consider the timing of the examination, as early assessments after injury may be less reliable 3
- Ensure adequate training of examiners to achieve high interrater reliability 3
Common Pitfalls to Avoid
- Incomplete motor testing - always assess both sides for comparison 2
- Failure to account for systemic factors that may affect neurological status (hypotension, hypoxemia) 3
- Inaccurate initial examination due to patient factors (uncooperativeness, intoxication, cognitive impairment) 3
- Neglecting to repeat examinations to detect neurological deterioration 3
Following this systematic approach ensures a comprehensive neurological examination that can guide diagnosis and management decisions across various clinical scenarios.