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Last updated: October 23, 2025View editorial policy

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Differential Diagnosis for Back Pain and Spot on Back

  • Single most likely diagnosis
    • Pilondial cyst: The patient's presentation of a spot on the back that is hurting more with back pain, especially after a fall, is consistent with a pilonidal cyst. These cysts can become inflamed and painful, especially with trauma or pressure on the area.
  • Other Likely diagnoses
    • Furuncle or abscess: A boil or abscess in the area could cause similar symptoms, especially if it becomes infected and inflamed.
    • Hematoma: The patient's history of falling down and hurting their back could have resulted in a hematoma, which could be causing the pain and swelling.
    • Contusion: A bruise from the fall could also be causing the pain and discomfort.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Epidural abscess: Although less likely, an epidural abscess is a serious and potentially life-threatening condition that could present with back pain and a focal spot of pain.
    • Spinal epidural hematoma: A hematoma in the spinal epidural space could compress the spinal cord and cause serious neurological symptoms.
    • Osteomyelitis: An infection of the bone could cause pain and swelling in the area, and if left untreated, could lead to serious complications.
  • Rare diagnoses
    • Spinal tumor: A tumor in the spine could cause back pain and a focal spot of pain, although this would be a less common cause of the patient's symptoms.
    • Cauda equina syndrome: A rare condition caused by compression of the nerves in the lower spine, which could present with back pain and neurological symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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