What is the recommended dosage of omeprazole for the treatment of gastritis?

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From the FDA Drug Label

Table 1: Recommended Dosage Regimen of Omeprazole in Adults by Indication Indication Dosage of Omeprazole Treatment Duration ... Active Benign Gastric Ulcer 40 mg once daily 4 to 8 weeks

The recommended dosage of omeprazole for the treatment of gastritis, specifically Active Benign Gastric Ulcer, is 40 mg once daily for 4 to 8 weeks 1.

From the Research

Recommended Dosage of Omeprazole for Gastritis

The recommended dosage of omeprazole for the treatment of gastritis is not explicitly stated in the provided studies. However, the following information can be gathered:

  • For the treatment of duodenal and gastric ulcer, omeprazole has been used at a dosage of 30-40 mg once daily 2.
  • In patients with Zollinger-Ellison syndrome, the recommended starting dose of omeprazole is 60 mg/day, but it has been shown that the maintenance dose could be safely reduced to 20 mg once or twice a day in more than two-thirds of patients 3.
  • In patients with duodenal ulcer, omeprazole has been used at a dosage of 20 mg twice a day for 8 weeks, resulting in complete healing of the ulcer and significant reduction in Helicobacter pylori density and urease activity 4.
  • In children, omeprazole has been administered at dosages of 5 to 80 mg/d (0.2-3.5 mg/kg/d) for the treatment of erosive esophagitis, gastric ulcer, duodenal ulcer, and Helicobacter pylori infection, with an initial dose of 1 mg/kg per day reported to heal esophagitis and provide relief of symptoms of gastroesophageal reflux disease 5.

Key Points

  • Omeprazole dosage for gastritis is not explicitly stated in the provided studies.
  • Dosages of 20-40 mg once daily have been used for the treatment of duodenal and gastric ulcer 2.
  • A starting dose of 60 mg/day is recommended for patients with Zollinger-Ellison syndrome, with potential reduction to 20 mg once or twice a day for maintenance 3.
  • Omeprazole has been effective in reducing Helicobacter pylori density and urease activity in patients with duodenal ulcer 4.
  • In children, omeprazole has been administered at various dosages for the treatment of acid-related disorders, with an initial dose of 1 mg/kg per day reported to be effective 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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