Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Burning Feet

  • Single most likely diagnosis
    • Diabetes Mellitus: This is often the first consideration for burning feet due to the high prevalence of diabetic neuropathy, which can cause burning sensations in the feet.
  • Other Likely diagnoses
    • Peripheral Artery Disease (PAD): Reduced blood flow to the feet can cause pain, burning, or heaviness, especially when walking.
    • Vitamin B12 Deficiency: A deficiency in vitamin B12 can lead to neuropathy, which may manifest as burning feet.
    • Alcohol Abuse: Chronic alcohol abuse can lead to alcoholic neuropathy, characterized by burning sensations in the feet.
    • Hypothyroidism: Some patients with hypothyroidism may experience burning sensations in their feet, though this is less common.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Guillain-Barré Syndrome: An autoimmune disorder that can lead to rapid-onset muscle weakness and neuropathy, which might start with burning sensations in the feet.
    • Heavy Metal Poisoning (e.g., arsenic, lead): Certain heavy metals can cause neuropathy, leading to burning sensations in the feet.
    • Lyme Disease: In its later stages, Lyme disease can cause neuropathy, which might include burning feet.
  • Rare diagnoses
    • Charcot-Marie-Tooth Disease: A group of inherited disorders that affect the peripheral nerves, potentially causing burning sensations in the feet.
    • Fabry Disease: A genetic disorder that can lead to neuropathic pain, including burning sensations in the feet.
    • Erythromelalgia: A disorder characterized by burning pain, heat, and redness in the hands and feet, often as a result of myeloproliferative disorders or as a primary condition.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.