MenB Vaccine Availability for Teenagers in Newfoundland, Canada
Yes, meningococcal B (MenB) vaccines are available for teenagers in Newfoundland, Canada, though they are not part of the routine immunization schedule and would require shared clinical decision-making between healthcare providers and patients/parents. 1
MenB Vaccine Overview
- Two MenB vaccines are licensed for use in individuals 10-25 years of age: Bexsero (MenB-4C) and Trumenba (MenB-FHbp) 1
- Bexsero requires a 2-dose series administered 1 month apart 1
- Trumenba can be given as either a 2-dose series (0 and 6 months) or a 3-dose series (0,2, and 6 months), with the 3-dose series recommended for those at increased risk 1
- These vaccines specifically target meningococcal serogroup B, which now causes approximately 40% of all meningococcal disease cases in adolescents and young adults 1
Current Recommendations for MenB Vaccination
MenB vaccines are not routinely recommended for all adolescents in Canada 2
They are recommended for persons 10 years and older at increased risk of meningococcal disease, including: 1
- Individuals with persistent complement component deficiencies
- Persons with anatomic or functional asplenia, including sickle cell disease
- Microbiologists who routinely work with N. meningitidis
- Persons in outbreak settings
For adolescents without risk factors, MenB vaccination may be administered based on shared clinical decision-making between healthcare providers and patients/parents 1
If administered, the preferred age for MenB vaccination is 16-18 years 1
Considerations for Vaccination Decision
Healthcare providers should discuss the following factors when considering MenB vaccination: 1
- The serious nature of meningococcal infections, with high rates of death and permanent sequelae
- The relatively low number of serogroup B meningococcal disease cases
- Increased risk among college students, especially freshmen living in residence halls
- The protection provided by MenB vaccines against most strains of serogroup B N. meningitidis
- The relatively short duration of protection (antibody waning within 1-2 years)
- Evidence suggesting MenB vaccination provides individual protection but limited herd immunity 1
Important Clinical Considerations
- MenB vaccines are different from MenACWY vaccines, which protect against serogroups A, C, W, and Y 3
- For complete protection against all major disease-causing meningococcal serogroups, both MenB and MenACWY vaccines would be needed 3
- The vaccines are not interchangeable - if starting a series with one product, the same product must be used to complete the series 1
- Cost-effectiveness analyses suggest that MenB vaccination is unlikely to meet widely accepted cost-effectiveness thresholds due to low disease incidence 4
Accessing MenB Vaccines in Newfoundland
- While not part of the routine immunization schedule, MenB vaccines can be obtained through prescription from healthcare providers 2
- Patients/parents would likely need to pay out-of-pocket unless they have private insurance coverage, as these vaccines are not publicly funded for routine use in most Canadian provinces 2, 5