Kawasaki Disease: An acute febrile illness that predominantly affects children, characterized by vasculitis of medium and small-sized arteries, particularly the coronary arteries. It is known for causing multiple vascular dilations and aneurysms, making it a prime consideration in pediatric cases.

Atherosclerosis: While more commonly associated with arterial stenosis, advanced atherosclerosis can lead to weakening of the arterial wall, resulting in aneurysm formation. This condition is more typical in older adults and those with risk factors such as hypertension, smoking, and hyperlipidemia.
Vasculitis (e.g., Takayasu Arteritis, Giant Cell Arteritis): These conditions involve inflammation of the blood vessels and can lead to aneurysm formation due to the weakening of the vascular wall. They are less common than atherosclerosis but are important to consider, especially in patients with systemic symptoms.
Connective Tissue Disorders (e.g., Marfan Syndrome, Ehlers-Danlos Syndrome): These genetic disorders affect the body's connective tissue, which provides support to various structures, including blood vessels. Patients with these conditions are at increased risk of developing aneurysms due to the inherent weakness in their vascular walls.

Infectious Aortitis: Infection of the aortic wall, which can be caused by bacteria (e.g., Salmonella, Staphylococcus), fungi, or other pathogens. This condition is rare but can lead to rapid progression of aneurysm and rupture if not promptly treated.
Trauma: Physical injury to blood vessels can cause aneurysm formation, either immediately or as a delayed complication. Recognizing trauma as a potential cause is crucial for timely and appropriate management.
Vascular Ehlers-Danlos Syndrome: A subtype of Ehlers-Danlos Syndrome that specifically affects the blood vessels, leading to a high risk of rupture and significant morbidity if not identified and managed properly.

Pseudoxanthoma Elasticum (PXE): A genetic disorder that affects the elastic fibers present in the skin, eyes, and cardiovascular system, leading to vascular complications, including aneurysms.
Loeys-Dietz Syndrome: A rare genetic disorder characterized by aneurysms, arterial tortuosity, and other systemic features. It is caused by mutations in the TGFBR1 or TGFBR2 genes.
Arterial Tortuosity Syndrome: A rare condition characterized by tortuous arteries and aneurysm formation, often diagnosed in childhood. It is associated with mutations in the SLC2A10 gene.